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Hedgehog-GLI and Notch Pathways Sustain Chemoresistance and Invasiveness in Colorectal Cancer and Their Inhibition Restores Chemotherapy Efficacy.
Citarella A, Catanzaro G, Besharat ZM, Trocchianesi S, Barbagallo F, Gosti G, Leonetti M, Di Fiore A, Coppola L, Autilio TM, Spinello Z, Vacca A, De Smaele E, Venneri MA, Ferretti E, Masuelli L, Po A. Citarella A, et al. Among authors: de smaele e. Cancers (Basel). 2023 Feb 25;15(5):1471. doi: 10.3390/cancers15051471. Cancers (Basel). 2023. PMID: 36900263 Free PMC article.
SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment.
Molfetta R, Lecce M, Milito ND, Putro E, Pietropaolo G, Marangio C, Scarno G, Moretti M, De Smaele E, Santini T, Bernardini G, Sciumè G, Santoni A, Paolini R. Molfetta R, et al. Among authors: de smaele e. Cell Death Dis. 2023 Sep 20;14(9):616. doi: 10.1038/s41419-023-06139-7. Cell Death Dis. 2023. PMID: 37730723 Free PMC article.
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice.
Arena A, Romeo MA, Po A, Benedetti R, Gilardini Montani MS, Gonnella R, Santarelli R, Gaeta A, De Smaele E, Cirone M. Arena A, et al. Among authors: de smaele e. Microbiol Spectr. 2023 Dec 12;11(6):e0263623. doi: 10.1128/spectrum.02636-23. Epub 2023 Oct 26. Microbiol Spectr. 2023. PMID: 37882554 Free PMC article.
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, Zazzeroni F, Gallo R, Masuelli L, Napolitano M, Maroder M, Modesti A, Giangaspero F, Screpanti I, Alesse E, Gulino A. Di Marcotullio L, et al. Among authors: de smaele e. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10833-8. doi: 10.1073/pnas.0400690101. Epub 2004 Jul 12. Proc Natl Acad Sci U S A. 2004. PMID: 15249678 Free PMC article.
Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets.
Ferretti E, Di Marcotullio L, Gessi M, Mattei T, Greco A, Po A, De Smaele E, Giangaspero F, Riccardi R, Di Rocco C, Pazzaglia S, Maroder M, Alimandi M, Screpanti I, Gulino A. Ferretti E, et al. Among authors: de smaele e. Oncogene. 2006 Nov 23;25(55):7267-73. doi: 10.1038/sj.onc.1209716. Epub 2006 Jul 31. Oncogene. 2006. PMID: 16878160
83 results