DeGrado WF - Search Results

1

Short peptides self-assemble to produce catalytic amyloids.

Rufo CM, Moroz YS, Moroz OV, Stöhr J, Smith TA, Hu X, DeGrado WF, Korendovych IV. Rufo CM, et al. Among authors: degrado wf. Nat Chem. 2014 Apr;6(4):303-9. doi: 10.1038/nchem.1894. Epub 2014 Mar 16. Nat Chem. 2014. PMID: 24651196 Free PMC article.

2

Computational design of a self-assembling β-peptide oligomer.

Korendovych IV, Kim YH, Ryan AH, Lear JD, Degrado WF, Shandler SJ. Korendovych IV, et al. Among authors: degrado wf. Org Lett. 2010 Nov 19;12(22):5142-5. doi: 10.1021/ol102092r. Epub 2010 Oct 14. Org Lett. 2010. PMID: 20945888 Free PMC article.

3

De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex.

Korendovych IV, Senes A, Kim YH, Lear JD, Fry HC, Therien MJ, Blasie JK, Walker FA, Degrado WF. Korendovych IV, et al. Among authors: degrado wf. J Am Chem Soc. 2010 Nov 10;132(44):15516-8. doi: 10.1021/ja107487b. J Am Chem Soc. 2010. PMID: 20945900 Free PMC article.

4

Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation.

Jo H, Culik RM, Korendovych IV, Degrado WF, Gai F. Jo H, et al. Among authors: degrado wf. Biochemistry. 2010 Dec 14;49(49):10354-6. doi: 10.1021/bi101711a. Epub 2010 Nov 17. Biochemistry. 2010. PMID: 21077670 Free PMC article.

5

Design of a switchable eliminase.

Korendovych IV, Kulp DW, Wu Y, Cheng H, Roder H, DeGrado WF. Korendovych IV, et al. Among authors: degrado wf. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6823-7. doi: 10.1073/pnas.1018191108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482808 Free PMC article.

6

Residue-specific vibrational echoes yield 3D structures of a transmembrane helix dimer.

Remorino A, Korendovych IV, Wu Y, DeGrado WF, Hochstrasser RM. Remorino A, et al. Among authors: degrado wf. Science. 2011 Jun 3;332(6034):1206-9. doi: 10.1126/science.1202997. Science. 2011. PMID: 21636774 Free PMC article.

7

Environment- and sequence-dependence of helical type in membrane-spanning peptides composed of β3-amino acids.

Korendovych IV, Shandler SJ, Montalvo GL, DeGrado WF. Korendovych IV, et al. Among authors: degrado wf. Org Lett. 2011 Jul 1;13(13):3474-7. doi: 10.1021/ol201218y. Epub 2011 Jun 9. Org Lett. 2011. PMID: 21651308 Free PMC article.

8

Computational design of a β-peptide that targets transmembrane helices.

Shandler SJ, Korendovych IV, Moore DT, Smith-Dupont KB, Streu CN, Litvinov RI, Billings PC, Gai F, Bennett JS, DeGrado WF. Shandler SJ, et al. Among authors: degrado wf. J Am Chem Soc. 2011 Aug 17;133(32):12378-81. doi: 10.1021/ja204215f. Epub 2011 Jul 22. J Am Chem Soc. 2011. PMID: 21780757 Free PMC article.

9

2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel.

Ghosh A, Wang J, Moroz YS, Korendovych IV, Zanni M, DeGrado WF, Gai F, Hochstrasser RM. Ghosh A, et al. Among authors: degrado wf. J Chem Phys. 2014 Jun 21;140(23):235105. doi: 10.1063/1.4881188. J Chem Phys. 2014. PMID: 24952572 Free PMC article.

10

Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.

Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. Stöhr J, et al. Among authors: degrado wf. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10329-34. doi: 10.1073/pnas.1408968111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982137 Free PMC article.

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