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Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract.
Sullivan MJ, Goh KGK, Thapa R, Chattopadhyay D, Ipe DS, Duell BL, Katupitiya L, Gosling D, Acharya D, Ulett GC. Sullivan MJ, et al. Among authors: gosling d. Virulence. 2021 Dec;12(1):3015-3027. doi: 10.1080/21505594.2021.1989252. Virulence. 2021. PMID: 34643172 Free PMC article.
Restriction of chronic Escherichia coli urinary tract infection depends upon T cell-derived interleukin-17, a deficiency of which predisposes to flagella-driven bacterial persistence.
Chamoun MN, Sullivan MJ, Goh KGK, Acharya D, Ipe DS, Katupitiya L, Gosling D, Peters KM, Sweet MJ, Sester DP, Schembri MA, Ulett GC. Chamoun MN, et al. Among authors: gosling d. FASEB J. 2020 Nov;34(11):14572-14587. doi: 10.1096/fj.202000760R. Epub 2020 Sep 9. FASEB J. 2020. PMID: 32901999
Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5.
Acharya D, Sullivan MJ, Duell BL, Goh KGK, Katupitiya L, Gosling D, Chamoun MN, Kakkanat A, Chattopadhyay D, Crowley M, Crossman DK, Schembri MA, Ulett GC. Acharya D, et al. Among authors: gosling d. mSphere. 2019 Nov 27;4(6):e00545-19. doi: 10.1128/mSphere.00545-19. mSphere. 2019. PMID: 31776239 Free PMC article.