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Page 1
HLF expression defines the human hematopoietic stem cell state.
Lehnertz B, Chagraoui J, MacRae T, Tomellini E, Corneau S, Mayotte N, Boivin I, Durand A, Gracias D, Sauvageau G. Lehnertz B, et al. Among authors: gracias d. Blood. 2021 Dec 23;138(25):2642-2654. doi: 10.1182/blood.2021010745. Blood. 2021. PMID: 34499717 Free article.
Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk.
Wang X, Nissen M, Gracias D, Kusakabe M, Simkin G, Jiang A, Duns G, Sarkozy C, Hilton L, Chavez EA, Segat GC, Wong R, Kim J, Aoki T, Islam R, May C, Hung S, Tyshchenko K, Brinkman RR, Hirst M, Karsan A, Freeman C, Sehn LH, Morin RD, Roth AJ, Savage KJ, Craig JW, Shah SP, Steidl C, Scott DW, Weng AP. Wang X, et al. Among authors: gracias d. Nat Commun. 2022 Nov 9;13(1):6772. doi: 10.1038/s41467-022-34408-0. Nat Commun. 2022. PMID: 36351924 Free PMC article.
SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia.
Moison C, Gracias D, Schmitt J, Girard S, Spinella JF, Fortier S, Boivin I, Mendoza-Sanchez R, Thavonekham B, MacRae T, Mayotte N, Bonneil E, Wittman M, Carmichael J, Ruel R, Thibault P, Hébert J, Marinier A, Sauvageau G. Moison C, et al. Among authors: gracias d. Sci Adv. 2024 Mar 22;10(12):eadl4018. doi: 10.1126/sciadv.adl4018. Epub 2024 Mar 22. Sci Adv. 2024. PMID: 38517966 Free PMC article.
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.
Krosl J, Bordeleau ME, Moison C, MacRae T, Boivin I, Mayotte N, Gracias D, Baccelli I, Lavallée VP, Bisaillon R, Lehnertz B, Mendoza-Sanchez R, Ruel R, Bertomeu T, Coulombe-Huntington J, Boucher G, Noronha N, Pabst C, Tyers M, Gendron P, Lemieux S, Barabé F, Marinier A, Hébert J, Sauvageau G. Krosl J, et al. Among authors: gracias d. Blood Adv. 2022 Jan 25;6(2):509-514. doi: 10.1182/bloodadvances.2021006047. Blood Adv. 2022. PMID: 34731885 Free PMC article.
A tubulin binding molecule drives differentiation of acute myeloid leukemia cells.
Jackson TR, Vuorinen A, Josa-Culleré L, Madden KS, Conole D, Cogswell TJ, Wilkinson IVL, Kettyle LM, Zhang D, O'Mahony A, Gracias D, McCall L, Westwood R, Terstappen GC, Davies SG, Tate EW, Wynne GM, Vyas P, Russell AJ, Milne TA. Jackson TR, et al. Among authors: gracias d. iScience. 2022 Jul 19;25(8):104787. doi: 10.1016/j.isci.2022.104787. eCollection 2022 Aug 19. iScience. 2022. PMID: 35992086 Free PMC article.
Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.
Giambra V, Gusscott S, Gracias D, Song R, Lam SH, Panelli P, Tyshchenko K, Jenkins CE, Hoofd C, Lorzadeh A, Carles A, Hirst M, Eaves CJ, Weng AP. Giambra V, et al. Among authors: gracias d. Cell Stem Cell. 2018 Nov 1;23(5):714-726.e7. doi: 10.1016/j.stem.2018.08.018. Epub 2018 Sep 27. Cell Stem Cell. 2018. PMID: 30269902 Free article.
Single Cell Phenotypic Profiling of 27 DLBCL Cases Reveals Marked Intertumoral and Intratumoral Heterogeneity.
Nissen MD, Kusakabe M, Wang X, Simkin G, Gracias D, Tyshchenko K, Hill A, Meskas J, Hung S, Chavez EA, Ennishi D, Aoki T, Sarkozy C, Connors JM, Farinha P, Slack GW, Gascoyne RD, Brinkman RR, Scott DW, Steidl C, Weng AP. Nissen MD, et al. Among authors: gracias d. Cytometry A. 2020 Jun;97(6):620-629. doi: 10.1002/cyto.a.23919. Epub 2019 Oct 22. Cytometry A. 2020. PMID: 31637838 Free article.
Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling.
Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP. Giambra V, et al. Among authors: gracias d. Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1. Blood. 2015. PMID: 25934477 Free PMC article.