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PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.
J Exp Med. 2018 Dec 3;215(12):3094-3114. doi: 10.1084/jem.20180570. Epub 2018 Nov 7.
J Exp Med. 2018.
PMID: 30404791
Free PMC article.
Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.
Pouliot GP, Degar J, Hinze L, Kochupurakkal B, Vo CD, Burns MA, Moreau L, Ganesa C, Roderick J, Peirs S, Menten B, Loh ML, Hunger SP, Silverman LB, Harris MH, Stevenson KE, Weinstock DM, Weng AP, Van Vlierberghe P, D'Andrea AD, Gutierrez A.
Pouliot GP, et al. Among authors: degar j.
PLoS One. 2019 Nov 13;14(11):e0221288. doi: 10.1371/journal.pone.0221288. eCollection 2019.
PLoS One. 2019.
PMID: 31721781
Free PMC article.
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Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias.
Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E, Stanulla M, Gregory RI, Bauer DE, Wagner FF, Stegmaier K, Gutierrez A.
Hinze L, et al. Among authors: degar j.
Cancer Cell. 2019 Apr 15;35(4):664-676.e7. doi: 10.1016/j.ccell.2019.03.004.
Cancer Cell. 2019.
PMID: 30991026
Free PMC article.
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Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy.
Hinze L, Labrosse R, Degar J, Han T, Schatoff EM, Schreek S, Karim S, McGuckin C, Sacher JR, Wagner F, Stanulla M, Yuan C, Sicinska E, Giannakis M, Ng K, Dow LE, Gutierrez A.
Hinze L, et al. Among authors: degar j.
Cancer Discov. 2020 Nov;10(11):1690-1705. doi: 10.1158/2159-8290.CD-19-1472. Epub 2020 Jul 23.
Cancer Discov. 2020.
PMID: 32703769
Free PMC article.
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Supramolecular assembly of GSK3α as a cellular response to amino acid starvation.
Hinze L, Schreek S, Zeug A, Ibrahim NK, Fehlhaber B, Loxha L, Cinar B, Ponimaskin E, Degar J, McGuckin C, Chiosis G, Eckert C, Cario G, Bornhauser B, Bourquin JP, Stanulla M, Gutierrez A.
Hinze L, et al. Among authors: degar j.
Mol Cell. 2022 Aug 4;82(15):2858-2870.e8. doi: 10.1016/j.molcel.2022.05.025. Epub 2022 Jun 21.
Mol Cell. 2022.
PMID: 35732190
Free PMC article.
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