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The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.
Sappington PL, Cruz RJ Jr, Harada T, Yang R, Han Y, Englert JA, Ajami AA, Killeen ME, Delude RL, Fink MP. Sappington PL, et al. Among authors: delude rl. Biochem Pharmacol. 2005 Nov 25;70(11):1579-92. doi: 10.1016/j.bcp.2005.08.015. Epub 2005 Oct 13. Biochem Pharmacol. 2005. PMID: 16226725
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