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Crystal structure of the α1B-adrenergic receptor reveals molecular determinants of selective ligand recognition.
Nat Commun. 2022 Jan 19;13(1):382. doi: 10.1038/s41467-021-27911-3.
Nat Commun. 2022.
PMID: 35046410
Free PMC article.
A cleavable ligand column for the rapid isolation of large quantities of homogeneous and functional neurotensin receptor 1 variants from E. coli.
Egloff P, Deluigi M, Heine P, Balada S, Plückthun A.
Egloff P, et al. Among authors: deluigi m.
Protein Expr Purif. 2015 Apr;108:106-114. doi: 10.1016/j.pep.2014.10.006. Epub 2014 Oct 20.
Protein Expr Purif. 2015.
PMID: 25461958
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Determinants of Ligand Subtype-Selectivity at α1A-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR.
Yong KJ, Vaid TM, Shilling PJ, Wu FJ, Williams LM, Deluigi M, Plückthun A, Bathgate RAD, Gooley PR, Scott DJ.
Yong KJ, et al. Among authors: deluigi m.
ACS Chem Biol. 2018 Apr 20;13(4):1090-1102. doi: 10.1021/acschembio.8b00191. Epub 2018 Mar 22.
ACS Chem Biol. 2018.
PMID: 29537256
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Optimizing the α1B-adrenergic receptor for solution NMR studies.
Schuster M, Deluigi M, Pantić M, Vacca S, Baumann C, Scott DJ, Plückthun A, Zerbe O.
Schuster M, et al. Among authors: deluigi m.
Biochim Biophys Acta Biomembr. 2020 Oct 1;1862(10):183354. doi: 10.1016/j.bbamem.2020.183354. Epub 2020 May 13.
Biochim Biophys Acta Biomembr. 2020.
PMID: 32413443
Free article.
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Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Deluigi M, Klipp A, Klenk C, Merklinger L, Eberle SA, Morstein L, Heine P, Mittl PRE, Ernst P, Kamenecka TM, He Y, Vacca S, Egloff P, Honegger A, Plückthun A.
Deluigi M, et al.
Sci Adv. 2021 Jan 27;7(5):eabe5504. doi: 10.1126/sciadv.abe5504. Print 2021 Jan.
Sci Adv. 2021.
PMID: 33571132
Free PMC article.
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Side-chain dynamics of the α1B -adrenergic receptor determined by NMR via methyl relaxation.
Baumann C, Chiang WC, Valsecchi R, Jurt S, Deluigi M, Schuster M, Rosengren KJ, Plückthun A, Zerbe O.
Baumann C, et al. Among authors: deluigi m.
Protein Sci. 2023 Nov;32(11):e4801. doi: 10.1002/pro.4801.
Protein Sci. 2023.
PMID: 37805830
Free PMC article.
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Identification of a Novel Subtype-Selective α1B-Adrenoceptor Antagonist.
Abdul-Ridha A, de Zhang LA, Betrie AH, Deluigi M, Vaid TM, Whitehead A, Zhang Y, Davis B, Harris R, Simmonite H, Hubbard RE, Gooley PR, Plückthun A, Bathgate RAD, Chalmers DK, Scott DJ.
Abdul-Ridha A, et al. Among authors: deluigi m.
ACS Chem Neurosci. 2024 Feb 7;15(3):671-684. doi: 10.1021/acschemneuro.3c00767. Epub 2024 Jan 18.
ACS Chem Neurosci. 2024.
PMID: 38238043
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Pseudodoubling of the optic disc.
Barboni P, Deluigi M, De Bonis C, Monetti G, Savini G, Zanini M.
Barboni P, et al. Among authors: deluigi m.
Arch Ophthalmol. 1998 Oct;116(10):1400-1. doi: 10.1001/archopht.116.10.1400.
Arch Ophthalmol. 1998.
PMID: 9790655
No abstract available.
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