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Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.
Kellaway SG, Potluri S, Keane P, Blair HJ, Ames L, Worker A, Chin PS, Ptasinska A, Derevyanko PK, Adamo A, Coleman DJL, Khan N, Assi SA, Krippner-Heidenreich A, Raghavan M, Cockerill PN, Heidenreich O, Bonifer C. Kellaway SG, et al. Among authors: derevyanko pk. Nat Commun. 2024 Feb 14;15(1):1359. doi: 10.1038/s41467-024-45691-4. Nat Commun. 2024. PMID: 38355578 Free PMC article.
One signal stimulates different transcriptional activation mechanisms.
Mazina MY, Kovalenko EV, Derevyanko PK, Nikolenko JV, Krasnov AN, Vorobyeva NE. Mazina MY, et al. Among authors: derevyanko pk. Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):178-189. doi: 10.1016/j.bbagrm.2018.01.016. Epub 2018 Feb 6. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 29410380
Mdm4 supports DNA replication in a p53-independent fashion.
Wohlberedt K, Klusmann I, Derevyanko PK, Henningsen K, Choo JAMY, Manzini V, Magerhans A, Giansanti C, Eischen CM, Jochemsen AG, Dobbelstein M. Wohlberedt K, et al. Among authors: derevyanko pk. Oncogene. 2020 Jun;39(25):4828-4843. doi: 10.1038/s41388-020-1325-1. Epub 2020 May 19. Oncogene. 2020. PMID: 32427989 Free PMC article.