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Page 1
Proprotein convertases: Key players in inflammation-related malignancies and metastasis.
Cancer Lett. 2020 Mar 31;473:50-61. doi: 10.1016/j.canlet.2019.12.027. Epub 2019 Dec 30.
Cancer Lett. 2020.
PMID: 31899298
Free PMC article.
Review.
Reprogramming immune cells activity by furin-like enzymes as emerging strategy for enhanced immunotherapy in cancer.
François A, Descarpentrie J, Badiola I, Siegfried G, Evrard S, Pernot S, Khatib AM.
François A, et al. Among authors: descarpentrie j.
Br J Cancer. 2023 Mar;128(7):1189-1195. doi: 10.1038/s41416-022-02073-1. Epub 2022 Dec 15.
Br J Cancer. 2023.
PMID: 36522477
Free PMC article.
Review.
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Proprotein convertases blockage up-regulates specifically metallothioneins coding genes in human colon cancer stem cells.
Gerovska D, García-Gallastegi P, Descarpentrie J, Crende O, Casado-Andrés M, Martín A, Eguia J, Khatib AM, Araúzo-Bravo MJ, Badiola I.
Gerovska D, et al. Among authors: descarpentrie j.
Biochim Biophys Acta Mol Cell Res. 2021 Mar;1868(3):118912. doi: 10.1016/j.bbamcr.2020.118912. Epub 2020 Nov 26.
Biochim Biophys Acta Mol Cell Res. 2021.
PMID: 33249002
Free article.
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ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation.
Soulet F, Bodineau C, Hooks KB, Descarpentrie J, Alves I, Dubreuil M, Mouchard A, Eugenie M, Hoepffner JL, López JJ, Rosado JA, Soubeyran I, Tomé M, Durán RV, Nikolski M, Villoutreix BO, Evrard S, Siegfried G, Khatib AM.
Soulet F, et al. Among authors: descarpentrie j.
JCI Insight. 2020 Jul 23;5(14):e129070. doi: 10.1172/jci.insight.129070.
JCI Insight. 2020.
PMID: 32516140
Free PMC article.
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Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors.
Descarpentrie J, Araúzo-Bravo MJ, He Z, François A, González Á, Garcia-Gallastegi P, Badiola I, Evrard S, Pernot S, Creemers JWM, Khatib AM.
Descarpentrie J, et al.
Cancers (Basel). 2022 Feb 25;14(5):1195. doi: 10.3390/cancers14051195.
Cancers (Basel). 2022.
PMID: 35267511
Free PMC article.
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Furin Prodomain ppFurin Enhances Ca2+ Entry Through Orai and TRPC6 Channels' Activation in Breast Cancer Cells.
López JJ, Siegfried G, Cantonero C, Soulet F, Descarpentrie J, Smani T, Badiola I, Pernot S, Evrard S, Rosado JA, Khatib AM.
López JJ, et al. Among authors: descarpentrie j.
Cancers (Basel). 2021 Apr 1;13(7):1670. doi: 10.3390/cancers13071670.
Cancers (Basel). 2021.
PMID: 33916304
Free PMC article.
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Inhibition of proprotein convertases activity results in repressed stemness and invasiveness of cancer stem cells in gastric cancer.
Zaafour A, Seeneevassen L, Nguyen TL, Genevois C, Nicolas N, Sifré E, Giese A, Porcheron C, Descarpentrie J, Dubus P, Khatib AM, Varon C.
Zaafour A, et al. Among authors: descarpentrie j.
Gastric Cancer. 2024 Mar;27(2):292-307. doi: 10.1007/s10120-023-01462-6. Epub 2024 Jan 27.
Gastric Cancer. 2024.
PMID: 38280128
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