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Page 1
Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.
Nikolaev SI, Vetiska S, Bonilla X, Boudreau E, Jauhiainen S, Rezai Jahromi B, Khyzha N, DiStefano PV, Suutarinen S, Kiehl TR, Mendes Pereira V, Herman AM, Krings T, Andrade-Barazarte H, Tung T, Valiante T, Zadeh G, Tymianski M, Rauramaa T, Ylä-Herttuala S, Wythe JD, Antonarakis SE, Frösen J, Fish JE, Radovanovic I. Nikolaev SI, et al. Among authors: distefano pv. N Engl J Med. 2018 Jan 18;378(3):250-261. doi: 10.1056/NEJMoa1709449. Epub 2018 Jan 3. N Engl J Med. 2018. PMID: 29298116 Free PMC article.
Circulating small extracellular vesicles mediate vascular hyperpermeability in diabetes.
Gustafson D, DiStefano PV, Wang XF, Wu R, Ghaffari S, Ching C, Rathnakumar K, Alibhai F, Syonov M, Fitzpatrick J, Boudreau E, Lau C, Galant N, Husain M, Li RK, Lee WL, Parekh RS, Monnier PP, Fish JE. Gustafson D, et al. Among authors: distefano pv. Diabetologia. 2024 Jun;67(6):1138-1154. doi: 10.1007/s00125-024-06120-9. Epub 2024 Mar 15. Diabetologia. 2024. PMID: 38489029 Free PMC article.
The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity.
Wang XF, Vigouroux R, Syonov M, Baglaenko Y, Nikolakopoulou AM, Ringuette D, Rus H, DiStefano PV, Dufour S, Shabanzadeh AP, Lee S, Mueller BK, Charish J, Harada H, Fish JE, Wither J, Wälchli T, Cloutier JF, Zlokovic BV, Carlen PL, Monnier PP. Wang XF, et al. Among authors: distefano pv. Nat Commun. 2024 Feb 3;15(1):1037. doi: 10.1038/s41467-024-45303-1. Nat Commun. 2024. PMID: 38310100 Free PMC article.
Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling.
Fish JE, Flores Suarez CP, Boudreau E, Herman AM, Gutierrez MC, Gustafson D, DiStefano PV, Cui M, Chen Z, De Ruiz KB, Schexnayder TS, Ward CS, Radovanovic I, Wythe JD. Fish JE, et al. Among authors: distefano pv. Circ Res. 2020 Aug 28;127(6):727-743. doi: 10.1161/CIRCRESAHA.119.316500. Epub 2020 Jun 17. Circ Res. 2020. PMID: 32552404 Free PMC article.
11 results