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Page 1
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting.
Chen K, Henn D, Januszyk M, Barrera JA, Noishiki C, Bonham CA, Griffin M, Tevlin R, Carlomagno T, Shannon T, Fehlmann T, Trotsyuk AA, Padmanabhan J, Sivaraj D, Perrault DP, Zamaleeva AI, Mays CJ, Greco AH, Kwon SH, Leeolou MC, Huskins SL, Steele SR, Fischer KS, Kussie HC, Mittal S, Mermin-Bunnell AM, Diaz Deleon NM, Lavin C, Keller A, Longaker MT, Gurtner GC. Chen K, et al. Among authors: diaz deleon nm. Sci Transl Med. 2022 May 18;14(645):eabj9152. doi: 10.1126/scitranslmed.abj9152. Epub 2022 May 18. Sci Transl Med. 2022. PMID: 35584231
Understanding Scarring in the Oral Mucosa.
Griffin MF, Fahy EJ, King M, Guardino N, Chen K, Abbas DB, Lavin CV, Diaz Deleon NM, Lorenz HP, Longaker MT, Wan DC. Griffin MF, et al. Among authors: diaz deleon nm. Adv Wound Care (New Rochelle). 2022 Oct;11(10):537-547. doi: 10.1089/wound.2021.0038. Epub 2021 Oct 12. Adv Wound Care (New Rochelle). 2022. PMID: 34470520 Free PMC article. Review.
Decellularized Adipose Matrices Can Alleviate Radiation-Induced Skin Fibrosis.
Adem S, Abbas DB, Lavin CV, Fahy EJ, Griffin M, Diaz Deleon NM, Borrelli MR, Mascharak S, Shen AH, Patel RA, Longaker MT, Nazerali RS, Wan DC. Adem S, et al. Among authors: diaz deleon nm. Adv Wound Care (New Rochelle). 2022 Oct;11(10):524-536. doi: 10.1089/wound.2021.0008. Epub 2021 Sep 6. Adv Wound Care (New Rochelle). 2022. PMID: 34346243 Free PMC article.
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models.
Griffin MF, Borrelli MR, Garcia JT, Januszyk M, King M, Lerbs T, Cui L, Moore AL, Shen AH, Mascharak S, Diaz Deleon NM, Adem S, Taylor WL, desJardins-Park HE, Gastou M, Patel RA, Duoto BA, Sokol J, Wei Y, Foster D, Chen K, Wan DC, Gurtner GC, Lorenz HP, Chang HY, Wernig G, Longaker MT. Griffin MF, et al. Among authors: diaz deleon nm. Sci Transl Med. 2021 Sep;13(609):eabb3312. doi: 10.1126/scitranslmed.abb3312. Epub 2021 Sep 1. Sci Transl Med. 2021. PMID: 34516825 Free PMC article.
Fat grafting rescues radiation-induced joint contracture.
Borrelli MR, Diaz Deleon NM, Adem S, Patel RA, Mascharak S, Shen AH, Irizarry D, Nguyen D, Momeni A, Longaker MT, Wan DC. Borrelli MR, et al. Among authors: diaz deleon nm. Stem Cells. 2020 Mar;38(3):382-389. doi: 10.1002/stem.3115. Epub 2019 Dec 3. Stem Cells. 2020. PMID: 31793745 Free PMC article.
The antifibrotic adipose-derived stromal cell: Grafted fat enriched with CD74+ adipose-derived stromal cells reduces chronic radiation-induced skin fibrosis.
Borrelli MR, Patel RA, Adem S, Diaz Deleon NM, Shen AH, Sokol J, Yen S, Chang EY, Nazerali R, Nguyen D, Momeni A, Wang KC, Longaker MT, Wan DC. Borrelli MR, et al. Among authors: diaz deleon nm. Stem Cells Transl Med. 2020 Nov;9(11):1401-1413. doi: 10.1002/sctm.19-0317. Epub 2020 Jun 20. Stem Cells Transl Med. 2020. PMID: 32563212 Free PMC article.
CD34+CD146+ adipose-derived stromal cells enhance engraftment of transplanted fat.
Borrelli MR, Patel RA, Blackshear C, Vistnes S, Diaz Deleon NM, Adem S, Shen AH, Sokol J, Momeni A, Nguyen D, Longaker MT, Wan DC. Borrelli MR, et al. Among authors: diaz deleon nm. Stem Cells Transl Med. 2020 Nov;9(11):1389-1400. doi: 10.1002/sctm.19-0195. Epub 2020 Jun 15. Stem Cells Transl Med. 2020. PMID: 32543083 Free PMC article.
A tension offloading patch mitigates dermal fibrosis induced by pro-fibrotic skin injections.
Talbott HE, Griffin MF, Mascharak S, Parker JBL, Kuhnert MM, Guo JL, Diaz Deleon NM, Lavin C, Abbas D, Guardino N, Morgan A, Valencia C, Cotterell A, Longaker MT, Wan DC. Talbott HE, et al. Among authors: diaz deleon nm. Res Sq [Preprint]. 2024 Mar 1:rs.3.rs-3915097. doi: 10.21203/rs.3.rs-3915097/v1. Res Sq. 2024. PMID: 38464040 Free PMC article. Preprint.
Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition.
Griffin MF, Talbott HE, Guardino NJ, Guo JL, Spielman AF, Chen K, Parker JBL, Mascharak S, Henn D, Liang N, King M, Cotterell AC, Bauer-Rowe KE, Abbas DB, Diaz Deleon NM, Sivaraj D, Fahy EJ, Downer M, Akras D, Berry C, Cook J, Quarto N, Klein OD, Lorenz HP, Gurtner GC, Januszyk M, Wan DC, Longaker MT. Griffin MF, et al. Among authors: diaz deleon nm. bioRxiv [Preprint]. 2023 Apr 4:2023.04.03.535302. doi: 10.1101/2023.04.03.535302. bioRxiv. 2023. PMID: 37066136 Free PMC article. Preprint.