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Lactate production is a prioritized feature of adipocyte metabolism.
Krycer JR, Quek LE, Francis D, Fazakerley DJ, Elkington SD, Diaz-Vegas A, Cooke KC, Weiss FC, Duan X, Kurdyukov S, Zhou PX, Tambar UK, Hirayama A, Ikeda S, Kamei Y, Soga T, Cooney GJ, James DE. Krycer JR, et al. J Biol Chem. 2020 Jan 3;295(1):83-98. doi: 10.1074/jbc.RA119.011178. Epub 2019 Nov 5. J Biol Chem. 2020. PMID: 31690627 Free PMC article.
Insulin signaling requires glucose to promote lipid anabolism in adipocytes.
Krycer JR, Quek LE, Francis D, Zadoorian A, Weiss FC, Cooke KC, Nelson ME, Diaz-Vegas A, Humphrey SJ, Scalzo R, Hirayama A, Ikeda S, Shoji F, Suzuki K, Huynh K, Giles C, Varney B, Nagarajan SR, Hoy AJ, Soga T, Meikle PJ, Cooney GJ, Fazakerley DJ, James DE. Krycer JR, et al. J Biol Chem. 2020 Sep 18;295(38):13250-13266. doi: 10.1074/jbc.RA120.014907. Epub 2020 Jul 28. J Biol Chem. 2020. PMID: 32723868 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33518012
[No title available]
[No authors listed] [No authors listed] PMID: 33518013
Dissecting the biology of mTORC1 beyond rapamycin.
Yang G, Francis D, Krycer JR, Larance M, Zhang Z, Novotny CJ, Diaz-Vegas A, Shokat KM, James DE. Yang G, et al. Among authors: diaz vegas a. Sci Signal. 2021 Sep 21;14(701):eabe0161. doi: 10.1126/scisignal.abe0161. Epub 2021 Sep 21. Sci Signal. 2021. PMID: 34546793 Free PMC article.
Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Yau B, Naghiloo S, Diaz-Vegas A, Carr AV, Van Gerwen J, Needham EJ, Jevon D, Chen SY, Hoehn KL, Brandon AE, Macia L, Cooney GJ, Shortreed MR, Smith LM, Keller MP, Thorn P, Larance M, James DE, Humphrey SJ, Kebede MA. Yau B, et al. Among authors: diaz vegas a. iScience. 2021 Sep 9;24(10):103099. doi: 10.1016/j.isci.2021.103099. eCollection 2021 Oct 22. iScience. 2021. PMID: 34622154 Free PMC article.
A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology.
Diaz-Vegas A, Norris DM, Jall-Rogg S, Cooke KC, Conway OJ, Shun-Shion AS, Duan X, Potter M, van Gerwen J, Baird HJ, Humphrey SJ, James DE, Fazakerley DJ, Burchfield JG. Diaz-Vegas A, et al. Life Sci Alliance. 2022 Oct 25;6(1):e202201585. doi: 10.26508/lsa.202201585. Print 2023 Jan. Life Sci Alliance. 2022. PMID: 36283703 Free PMC article.
26 results