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Translational relevance of SOS1 targeting for KRAS-mutant colorectal cancer.
Alem D, Yang X, Beato F, Sarcar B, Tassielli AF, Dai R, Hogenson TL, Park MA, Jiang K, Cai J, Yuan Y, Fernandez-Zapico ME, Tan AC, Fleming JB, Xie H. Alem D, et al. Mol Carcinog. 2023 Jul;62(7):1025-1037. doi: 10.1002/mc.23543. Epub 2023 Apr 12. Mol Carcinog. 2023. PMID: 37042566
New Nitric Oxide-Releasing Compounds as Promising Anti-Bladder Cancer Drugs.
Varela M, López M, Ingold M, Alem D, Perini V, Perelmuter K, Bollati-Fogolín M, López GV, Hernández P. Varela M, et al. Among authors: alem d. Biomedicines. 2023 Jan 12;11(1):199. doi: 10.3390/biomedicines11010199. Biomedicines. 2023. PMID: 36672707 Free PMC article.
Development of SOS1 Inhibitor-Based Degraders to Target KRAS-Mutant Colorectal Cancer.
Bian Y, Alem D, Beato F, Hogenson TL, Yang X, Jiang K, Cai J, Ma WW, Fernandez-Zapico M, Tan AC, Lawrence NJ, Fleming JB, Yuan Y, Xie H. Bian Y, et al. Among authors: alem d. J Med Chem. 2022 Dec 22;65(24):16432-16450. doi: 10.1021/acs.jmedchem.2c01300. Epub 2022 Dec 2. J Med Chem. 2022. PMID: 36459180 Free PMC article.
Neuroprotective effects of violacein in a model of inherited amyotrophic lateral sclerosis.
Olivera-Bravo S, Bolatto C, Otero Damianovich G, Stancov M, Cerri S, Rodríguez P, Boragno D, Hernández Mir K, Cuitiño MN, Larrambembere F, Isasi E, Alem D, Canclini L, Marco M, Davyt D, Díaz-Amarilla P. Olivera-Bravo S, et al. Among authors: alem d. Sci Rep. 2022 Mar 15;12(1):4439. doi: 10.1038/s41598-022-06470-7. Sci Rep. 2022. PMID: 35292673 Free PMC article.