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Page 1
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Perets R, Wyant GA, Muto KW, Bijron JG, Poole BB, Chin KT, Chen JY, Ohman AW, Stepule CD, Kwak S, Karst AM, Hirsch MS, Setlur SR, Crum CP, Dinulescu DM, Drapkin R. Perets R, et al. Among authors: dinulescu dm. Cancer Cell. 2013 Dec 9;24(6):751-65. doi: 10.1016/j.ccr.2013.10.013. Cancer Cell. 2013. PMID: 24332043 Free PMC article.
Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy.
Paraskar AS, Soni S, Chin KT, Chaudhuri P, Muto KW, Berkowitz J, Handlogten MW, Alves NJ, Bilgicer B, Dinulescu DM, Mashelkar RA, Sengupta S. Paraskar AS, et al. Among authors: dinulescu dm. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12435-40. doi: 10.1073/pnas.1007026107. Epub 2010 Jun 23. Proc Natl Acad Sci U S A. 2010. PMID: 20616005 Free PMC article.
Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity.
Sengupta P, Basu S, Soni S, Pandey A, Roy B, Oh MS, Chin KT, Paraskar AS, Sarangi S, Connor Y, Sabbisetti VS, Kopparam J, Kulkarni A, Muto K, Amarasiriwardena C, Jayawardene I, Lupoli N, Dinulescu DM, Bonventre JV, Mashelkar RA, Sengupta S. Sengupta P, et al. Among authors: dinulescu dm. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11294-9. doi: 10.1073/pnas.1203129109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733767 Free PMC article.
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.
McAuliffe SM, Morgan SL, Wyant GA, Tran LT, Muto KW, Chen YS, Chin KT, Partridge JC, Poole BB, Cheng KH, Daggett J Jr, Cullen K, Kantoff E, Hasselbatt K, Berkowitz J, Muto MG, Berkowitz RS, Aster JC, Matulonis UA, Dinulescu DM. McAuliffe SM, et al. Among authors: dinulescu dm. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):E2939-48. doi: 10.1073/pnas.1206400109. Epub 2012 Sep 27. Proc Natl Acad Sci U S A. 2012. PMID: 23019585 Free PMC article.
"Take it up a NOTCH": novel strategies for cancer therapy.
Morgan SL, Wyant GA, Dinulescu DM. Morgan SL, et al. Among authors: dinulescu dm. Cell Cycle. 2013 Jan 15;12(2):191-2. doi: 10.4161/cc.23375. Epub 2012 Jan 15. Cell Cycle. 2013. PMID: 23287472 Free PMC article. No abstract available.
Supramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacy.
Kulkarni AA, Roy B, Rao PS, Wyant GA, Mahmoud A, Ramachandran M, Sengupta P, Goldman A, Kotamraju VR, Basu S, Mashelkar RA, Ruoslahti E, Dinulescu DM, Sengupta S. Kulkarni AA, et al. Among authors: dinulescu dm. Cancer Res. 2013 Dec 1;73(23):6987-97. doi: 10.1158/0008-5472.CAN-12-4477. Epub 2013 Oct 11. Cancer Res. 2013. PMID: 24121488 Free PMC article.
The promise and challenge of ovarian cancer models.
Hasan N, Ohman AW, Dinulescu DM. Hasan N, et al. Among authors: dinulescu dm. Transl Cancer Res. 2015 Feb;4(1):14-28. doi: 10.3978/j.issn.2218-676X.2015.01.02. Transl Cancer Res. 2015. PMID: 26114093 Free PMC article.
Origin of clear cell carcinoma: nature or nurture?
Kolin DL, Dinulescu DM, Crum CP. Kolin DL, et al. Among authors: dinulescu dm. J Pathol. 2018 Feb;244(2):131-134. doi: 10.1002/path.5009. Epub 2018 Jan 2. J Pathol. 2018. PMID: 29178260
46 results