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Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids.
Horrocks MH, Lee SF, Gandhi S, Magdalinou NK, Chen SW, Devine MJ, Tosatto L, Kjaergaard M, Beckwith JS, Zetterberg H, Iljina M, Cremades N, Dobson CM, Wood NW, Klenerman D. Horrocks MH, et al. Among authors: dobson cm. ACS Chem Neurosci. 2016 Mar 16;7(3):399-406. doi: 10.1021/acschemneuro.5b00324. Epub 2016 Feb 4. ACS Chem Neurosci. 2016. PMID: 26800462 Free PMC article.
Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells.
Whiten DR, Zuo Y, Calo L, Choi ML, De S, Flagmeier P, Wirthensohn DC, Kundel F, Ranasinghe RT, Sanchez SE, Athauda D, Lee SF, Dobson CM, Gandhi S, Spillantini MG, Klenerman D, Horrocks MH. Whiten DR, et al. Among authors: dobson cm. Chembiochem. 2018 Oct 4;19(19):2033-2038. doi: 10.1002/cbic.201800209. Epub 2018 Sep 11. Chembiochem. 2018. PMID: 30051958 Free PMC article.
Quantifying Co-Oligomer Formation by α-Synuclein.
Iljina M, Dear AJ, Garcia GA, De S, Tosatto L, Flagmeier P, Whiten DR, Michaels TCT, Frenkel D, Dobson CM, Knowles TPJ, Klenerman D. Iljina M, et al. Among authors: dobson cm. ACS Nano. 2018 Nov 27;12(11):10855-10866. doi: 10.1021/acsnano.8b03575. Epub 2018 Oct 29. ACS Nano. 2018. PMID: 30371053 Free PMC article.
Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42.
Weiffert T, Meisl G, Flagmeier P, De S, Dunning CJR, Frohm B, Zetterberg H, Blennow K, Portelius E, Klenerman D, Dobson CM, Knowles TPJ, Linse S. Weiffert T, et al. Among authors: dobson cm. ACS Chem Neurosci. 2019 May 15;10(5):2374-2384. doi: 10.1021/acschemneuro.8b00676. Epub 2019 Mar 8. ACS Chem Neurosci. 2019. PMID: 30793584
Optical Structural Analysis of Individual α-Synuclein Oligomers.
Varela JA, Rodrigues M, De S, Flagmeier P, Gandhi S, Dobson CM, Klenerman D, Lee SF. Varela JA, et al. Among authors: dobson cm. Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4886-4890. doi: 10.1002/anie.201710779. Epub 2018 Mar 23. Angew Chem Int Ed Engl. 2018. PMID: 29342318 Free PMC article.
803 results