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Page 1
Senescence and aging: Causes, consequences, and therapeutic avenues.
J Cell Biol. 2018 Jan 2;217(1):65-77. doi: 10.1083/jcb.201708092. Epub 2017 Nov 7.
J Cell Biol. 2018.
PMID: 29114066
Free PMC article.
Review.
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells.
McHugh D, Sun B, Gutierrez-Muñoz C, Hernández-González F, Mellone M, Guiho R, Duran I, Pombo J, Pietrocola F, Birch J, Kallemeijn WW, Khadayate S, Dharmalingam G, Vernia S, Tate EW, Martínez-Barbera JP, Withers DJ, Thomas GJ, Serrano M, Gil J.
McHugh D, et al.
Nat Cell Biol. 2023 Dec;25(12):1804-1820. doi: 10.1038/s41556-023-01287-6. Epub 2023 Nov 27.
Nat Cell Biol. 2023.
PMID: 38012402
Free PMC article.
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Detection of senescence using machine learning algorithms based on nuclear features.
Duran I, Pombo J, Sun B, Gallage S, Kudo H, McHugh D, Bousset L, Barragan Avila JE, Forlano R, Manousou P, Heikenwalder M, Withers DJ, Vernia S, Goldin RD, Gil J.
Duran I, et al. Among authors: mchugh d.
Nat Commun. 2024 Feb 3;15(1):1041. doi: 10.1038/s41467-024-45421-w.
Nat Commun. 2024.
PMID: 38310113
Free PMC article.
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XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence.
Innes AJ, Sun B, Wagner V, Brookes S, McHugh D, Pombo J, Porreca RM, Dharmalingam G, Vernia S, Zuber J, Vannier JB, García-Escudero R, Gil J.
Innes AJ, et al. Among authors: mchugh d.
Genes Dev. 2021 Mar 1;35(5-6):379-391. doi: 10.1101/gad.343269.120. Epub 2021 Feb 18.
Genes Dev. 2021.
PMID: 33602872
Free PMC article.
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Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH.
Gallage S, Ali A, Barragan Avila JE, Herebian D, Karimi MM, Irvine EE, McHugh D, Schneider AT, Vucur M, Keitel V, Gil J, Withers DJ, Luedde T, Heikenwalder M.
Gallage S, et al. Among authors: mchugh d.
Cell Mol Gastroenterol Hepatol. 2022;13(3):875-878. doi: 10.1016/j.jcmgh.2021.11.012. Epub 2021 Dec 6.
Cell Mol Gastroenterol Hepatol. 2022.
PMID: 34883280
Free PMC article.
No abstract available.
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ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.
Valle-García D, Qadeer ZA, McHugh DS, Ghiraldini FG, Chowdhury AH, Hasson D, Dyer MA, Recillas-Targa F, Bernstein E.
Valle-García D, et al. Among authors: mchugh ds.
Epigenetics. 2016 Jun 2;11(6):398-414. doi: 10.1080/15592294.2016.1169351. Epub 2016 Mar 30.
Epigenetics. 2016.
PMID: 27029610
Free PMC article.
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