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Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.
Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL, Herenius M, Doorenspleet ME, Tak PP, Crusius JB, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PL, van de Laar M, Guchelaar HJ, Shadick NA, Allaart CF, Huizinga TW, Toes RE, Kimberly RP, Bridges SL Jr, Criswell LA, Moreland LW, Fonseca JE, de Vries N, Stranger BE, De Jager PL, Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Padyukov L, Coenen MJ, Karlson EW, Plenge RM. Cui J, et al. Among authors: doorenspleet me. PLoS Genet. 2013 Mar;9(3):e1003394. doi: 10.1371/journal.pgen.1003394. Epub 2013 Mar 28. PLoS Genet. 2013. PMID: 23555300 Free PMC article.
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.
Plenge RM, Greenberg JD, Mangravite LM, Derry JM, Stahl EA, Coenen MJ, Barton A, Padyukov L, Klareskog L, Gregersen PK, Mariette X, Moreland LW, Bridges SL Jr, de Vries N, Huizinga TW, Guchelaar HJ; International Rheumatoid Arthritis Consortium (INTERACT); Friend SH, Stolovitzky G. Plenge RM, et al. Nat Genet. 2013 May;45(5):468-9. doi: 10.1038/ng.2623. Nat Genet. 2013. PMID: 23619782 Free PMC article. No abstract available.
Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
Klarenbeek PL, Doorenspleet ME, Esveldt RE, van Schaik BD, Lardy N, van Kampen AH, Tak PP, Plenge RM, Baas F, de Bakker PI, de Vries N. Klarenbeek PL, et al. Among authors: doorenspleet me. PLoS One. 2015 Oct 30;10(10):e0140815. doi: 10.1371/journal.pone.0140815. eCollection 2015. PLoS One. 2015. PMID: 26517366 Free PMC article.
Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire.
Pollastro S, Klarenbeek PL, Doorenspleet ME, van Schaik BDC, Esveldt REE, Thurlings RM, Boumans MJH, Gerlag DM, Tak PP, Vos K, Baas F, van Kampen AHC, de Vries N. Pollastro S, et al. Among authors: doorenspleet me. Ann Rheum Dis. 2019 Oct;78(10):1339-1345. doi: 10.1136/annrheumdis-2018-214898. Epub 2019 Jun 19. Ann Rheum Dis. 2019. PMID: 31217169 Free PMC article.
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease.
Klarenbeek PL, de Hair MJ, Doorenspleet ME, van Schaik BD, Esveldt RE, van de Sande MG, Cantaert T, Gerlag DM, Baeten D, van Kampen AH, Baas F, Tak PP, de Vries N. Klarenbeek PL, et al. Among authors: doorenspleet me. Ann Rheum Dis. 2012 Jun;71(6):1088-93. doi: 10.1136/annrheumdis-2011-200612. Epub 2012 Jan 31. Ann Rheum Dis. 2012. PMID: 22294635
Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis.
Tak PP, Doorenspleet ME, de Hair MJH, Klarenbeek PL, van Beers-Tas MH, van Kampen AHC, van Schaardenburg D, Gerlag DM, Baas F, de Vries N. Tak PP, et al. Among authors: doorenspleet me. Ann Rheum Dis. 2017 Nov;76(11):1924-1930. doi: 10.1136/annrheumdis-2017-211351. Epub 2017 Aug 8. Ann Rheum Dis. 2017. PMID: 28790026 Free PMC article. Retracted.
Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years.
Klarenbeek PL, Remmerswaal EB, ten Berge IJ, Doorenspleet ME, van Schaik BD, Esveldt RE, Koch SD, ten Brinke A, van Kampen AH, Bemelman FJ, Tak PP, Baas F, de Vries N, van Lier RA. Klarenbeek PL, et al. Among authors: doorenspleet me. PLoS Pathog. 2012 Sep;8(9):e1002889. doi: 10.1371/journal.ppat.1002889. Epub 2012 Sep 27. PLoS Pathog. 2012. PMID: 23028307 Free PMC article.
Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing.
Reshetova P, van Schaik BD, Klarenbeek PL, Doorenspleet ME, Esveldt RE, Tak PP, Guikema JE, de Vries N, van Kampen AH. Reshetova P, et al. Among authors: doorenspleet me. Front Immunol. 2017 Mar 6;8:221. doi: 10.3389/fimmu.2017.00221. eCollection 2017. Front Immunol. 2017. PMID: 28321219 Free PMC article.
25 results