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Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
Dunlop DC, Bonomelli C, Mansab F, Vasiljevic S, Doores KJ, Wormald MR, Palma AS, Feizi T, Harvey DJ, Dwek RA, Crispin M, Scanlan CN. Dunlop DC, et al. Among authors: doores kj. Glycobiology. 2010 Jul;20(7):812-23. doi: 10.1093/glycob/cwq020. Epub 2010 Feb 24. Glycobiology. 2010. PMID: 20181792 Free PMC article.
A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Doores KJ, Fulton Z, Hong V, Patel MK, Scanlan CN, Wormald MR, Finn MG, Burton DR, Wilson IA, Davis BG. Doores KJ, et al. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17107-12. doi: 10.1073/pnas.1002717107. Epub 2010 Sep 17. Proc Natl Acad Sci U S A. 2010. PMID: 20852065 Free PMC article.
Broad neutralization coverage of HIV by multiple highly potent antibodies.
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, Wong CH, Phogat S, Wrin T, Simek MD; Protocol G Principal Investigators; Koff WC, Wilson IA, Burton DR, Poignard P. Walker LM, et al. Among authors: doores kj. Nature. 2011 Sep 22;477(7365):466-70. doi: 10.1038/nature10373. Nature. 2011. PMID: 21849977 Free PMC article.
114 results