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Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Sankhala RS, Dussupt V, Donofrio G, Gromowski GD, De La Barrera RA, Larocca RA, Mendez-Rivera L, Lee A, Choe M, Zaky W, Mantus G, Jensen JL, Chen WH, Gohain N, Bai H, McCracken MK, Mason RD, Leggat D, Slike BM, Tran U, Jian N, Abbink P, Peterson R, Mendes EA, Freitas de Oliveira Franca R, Calvet GA, Bispo de Filippis AM, McDermott A, Roederer M, Hernandez M, Albertus A, Davidson E, Doranz BJ, Rolland M, Robb ML, Lynch RM, Barouch DH, Jarman RG, Thomas SJ, Modjarrad K, Michael NL, Krebs SJ, Joyce MG. Sankhala RS, et al. Among authors: doranz bj. Cell Rep. 2023 Aug 29;42(8):112942. doi: 10.1016/j.celrep.2023.112942. Epub 2023 Aug 9. Cell Rep. 2023. PMID: 37561630 Free PMC article.
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, Mohan D, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Murphy M, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Doranz BJ, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Mascola JR, Holbrook MR, Nemazee D, Wilson IA, Tan J. Dacon C, et al. Among authors: doranz bj. Cell Host Microbe. 2023 Jun 14;31(6):1071-1072. doi: 10.1016/j.chom.2023.05.016. Cell Host Microbe. 2023. PMID: 37321165 Free PMC article. No abstract available.
Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques.
Sankhala RS, Lal KG, Jensen JL, Dussupt V, Mendez-Rivera L, Bai H, Wieczorek L, Mayer SV, Zemil M, Wagner DA, Townsley SM, Hajduczki A, Chang WC, Chen WH, Donofrio GC, Jian N, King HAD, Lorang CG, Martinez EJ, Rees PA, Peterson CE, Schmidt F, Hart TJ, Duso DK, Kummer LW, Casey SP, Williams JK, Kannan S, Slike BM, Smith L, Swafford I, Thomas PV, Tran U, Currier JR, Bolton DL, Davidson E, Doranz BJ, Hatziioannou T, Bieniasz PD, Paquin-Proulx D, Reiley WW, Rolland M, Sullivan NJ, Vasan S, Collins ND, Modjarrad K, Gromowski GD, Polonis VR, Michael NL, Krebs SJ, Joyce MG. Sankhala RS, et al. Among authors: doranz bj. Nat Commun. 2024 Jan 3;15(1):200. doi: 10.1038/s41467-023-44265-0. Nat Commun. 2024. PMID: 38172512 Free PMC article.
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.
Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Duran V, Rebellon-Sanchez DE, Sanz AM, Rosso F, Doranz BJ, Einav S, Matsen Iv FA, Goo L. Lubow J, et al. Among authors: doranz bj. PLoS Pathog. 2023 Oct 9;19(10):e1011722. doi: 10.1371/journal.ppat.1011722. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37812640 Free PMC article.
Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity.
Jensen JL, Sankhala RS, Dussupt V, Bai H, Hajduczki A, Lal KG, Chang WC, Martinez EJ, Peterson CE, Golub ES, Rees PA, Mendez-Rivera L, Zemil M, Kavusak E, Mayer SV, Wieczorek L, Kannan S, Doranz BJ, Davidson E, Yang ES, Zhang Y, Chen M, Choe M, Wang L, Gromowski GD, Koup RA, Michael NL, Polonis VR, Rolland M, Modjarrad K, Krebs SJ, Joyce MG. Jensen JL, et al. Among authors: doranz bj. J Virol. 2023 Jul 27;97(7):e0159622. doi: 10.1128/jvi.01596-22. Epub 2023 Jul 3. J Virol. 2023. PMID: 37395646 Free PMC article.
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.
Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Doranz BJ, Duran V, Sanchez DE, Sanz AM, Rosso F, Einav S, Matsen FA, Goo L. Lubow J, et al. Among authors: doranz bj. bioRxiv [Preprint]. 2023 Apr 10:2023.04.09.536175. doi: 10.1101/2023.04.09.536175. bioRxiv. 2023. PMID: 37090561 Free PMC article. Updated. Preprint.
Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes.
Chen EC, Gilchuk P, Zost SJ, Ilinykh PA, Binshtein E, Huang K, Myers L, Bonissone S, Day S, Kona CR, Trivette A, Reidy JX, Sutton RE, Gainza C, Diaz S, Williams JK, Selverian CN, Davidson E, Saphire EO, Doranz BJ, Castellana N, Bukreyev A, Carnahan RH, Crowe JE Jr. Chen EC, et al. Among authors: doranz bj. Cell Rep. 2023 Apr 25;42(4):112370. doi: 10.1016/j.celrep.2023.112370. Epub 2023 Apr 7. Cell Rep. 2023. PMID: 37029928 Free PMC article.
Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity.
Chen WH, Hajduczki A, Martinez EJ, Bai H, Matz H, Hill TM, Lewitus E, Chang WC, Dawit L, Peterson CE, Rees PA, Ajayi AB, Golub ES, Swafford I, Dussupt V, David S, Mayer SV, Soman S, Kuklis C, Corbitt C, King J, Choe M, Sankhala RS, Thomas PV, Zemil M, Wieczorek L, Hart T, Duso D, Kummer L, Yan L, Sterling SL, Laing ED, Broder CC, Williams JK, Davidson E, Doranz BJ, Krebs SJ, Polonis VR, Paquin-Proulx D, Rolland M, Reiley WW, Gromowski GD, Modjarrad K, Dooley H, Joyce MG. Chen WH, et al. Among authors: doranz bj. Nat Commun. 2023 Feb 3;14(1):580. doi: 10.1038/s41467-023-36106-x. Nat Commun. 2023. PMID: 36737435 Free PMC article.
Antibody specificity against highly conserved membrane protein Claudin 6 driven by single atomic contact point.
Screnci B, Stafford LJ, Barnes T, Shema K, Gilman S, Wright R, Al Absi S, Phillips T, Azuelos C, Slovik K, Murphy P, Harmon DB, Charpentier T, Doranz BJ, Rucker JB, Chambers R. Screnci B, et al. Among authors: doranz bj. iScience. 2022 Nov 24;25(12):105665. doi: 10.1016/j.isci.2022.105665. eCollection 2022 Dec 22. iScience. 2022. PMID: 36505931 Free PMC article.
120 results