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Year Number of Results
2019 3
2020 4
2021 4
2022 7
2023 6
2024 0

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Page 1
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: weikert d. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843 Free PMC article.
Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Hegron A, Peach CJ, Tonello R, Seemann P, Teng S, Latorre R, Huebner H, Weikert D, Rientjes J, Veldhuis NA, Poole DP, Jensen DD, Thomsen ARB, Schmidt BL, Imlach WL, Gmeiner P, Bunnett NW. Hegron A, et al. Among authors: weikert d. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2220979120. doi: 10.1073/pnas.2220979120. Epub 2023 May 22. Proc Natl Acad Sci U S A. 2023. PMID: 37216510 Free PMC article.
Fluorescent ligands for dopamine D2/D3 receptors.
Allikalt A, Purkayastha N, Flad K, Schmidt MF, Tabor A, Gmeiner P, Hübner H, Weikert D. Allikalt A, et al. Among authors: weikert d. Sci Rep. 2020 Dec 14;10(1):21842. doi: 10.1038/s41598-020-78827-9. Sci Rep. 2020. PMID: 33318558 Free PMC article.
Discovery of Novel Nonpeptidic PAR2 Ligands.
Klösel I, Schmidt MF, Kaindl J, Hübner H, Weikert D, Gmeiner P. Klösel I, et al. Among authors: weikert d. ACS Med Chem Lett. 2020 May 22;11(6):1316-1323. doi: 10.1021/acsmedchemlett.0c00154. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551018 Free PMC article.
Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.
El Hamdaoui Y, Zheng F, Fritz N, Ye L, Tran MA, Schwickert K, Schirmeister T, Braeuning A, Lichtenstein D, Hellmich UA, Weikert D, Heinrich M, Treccani G, Schäfer MKE, Nowak G, Nürnberg B, Alzheimer C, Müller CP, Friedland K. El Hamdaoui Y, et al. Among authors: weikert d. Mol Psychiatry. 2022 Dec;27(12):5070-5085. doi: 10.1038/s41380-022-01804-3. Epub 2022 Oct 12. Mol Psychiatry. 2022. PMID: 36224261 Free PMC article.
21 results