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The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties.
Tattersall L, Shah KM, Lath DL, Singh A, Down JM, De Marchi E, Williamson A, Di Virgilio F, Heymann D, Adinolfi E, Fraser WD, Green D, Lawson MA, Gartland A. Tattersall L, et al. Among authors: down jm. J Bone Oncol. 2021 Oct 20;31:100398. doi: 10.1016/j.jbo.2021.100398. eCollection 2021 Dec. J Bone Oncol. 2021. PMID: 35340569 Free PMC article.
Melphalan modifies the bone microenvironment by enhancing osteoclast formation.
Chai RC, McDonald MM, Terry RL, Kovačić N, Down JM, Pettitt JA, Mohanty ST, Shah S, Haffari G, Xu J, Gillespie MT, Rogers MJ, Price JT, Croucher PI, Quinn JMW. Chai RC, et al. Among authors: down jm. Oncotarget. 2017 Jul 10;8(40):68047-68058. doi: 10.18632/oncotarget.19152. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978095 Free PMC article.
The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma.
Crawford LJ, Campbell DC, Morgan JJ, Lawson MA, Down JM, Chauhan D, McAvera RM, Morris TC, Hamilton C, Krishnan A, Rajalingam K, Chantry AD, Irvine AE. Crawford LJ, et al. Among authors: down jm. Oncogene. 2020 Jul;39(27):5001-5014. doi: 10.1038/s41388-020-1345-x. Epub 2020 Jun 10. Oncogene. 2020. PMID: 32523091 Free PMC article.