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166 results

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Page 1
Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study.
Lotery AJ, Gibson J, Cree AJ, Downes SM, Harding SP, Rogers CA, Reeves BC, Ennis S, Chakravarthy U; Alternative Treatments to Inhibit VEGF in Patients with Age-Related Choroidal Neovascularisation (IVAN) Study Group. Lotery AJ, et al. Among authors: downes sm. Ophthalmology. 2013 Dec;120(12):2637-2643. doi: 10.1016/j.ophtha.2013.07.046. Epub 2013 Sep 23. Ophthalmology. 2013. PMID: 24070809 Clinical Trial.
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.
MacLaren RE, Groppe M, Barnard AR, Cottriall CL, Tolmachova T, Seymour L, Clark KR, During MJ, Cremers FP, Black GC, Lotery AJ, Downes SM, Webster AR, Seabra MC. MacLaren RE, et al. Among authors: downes sm. Lancet. 2014 Mar 29;383(9923):1129-37. doi: 10.1016/S0140-6736(13)62117-0. Epub 2014 Jan 16. Lancet. 2014. PMID: 24439297 Free PMC article. Clinical Trial.
Cost-effectiveness of ranibizumab and bevacizumab for age-related macular degeneration: 2-year findings from the IVAN randomised trial.
Dakin HA, Wordsworth S, Rogers CA, Abangma G, Raftery J, Harding SP, Lotery AJ, Downes SM, Chakravarthy U, Reeves BC; IVAN Study Investigators. Dakin HA, et al. Among authors: downes sm. BMJ Open. 2014 Jul 29;4(7):e005094. doi: 10.1136/bmjopen-2014-005094. BMJ Open. 2014. PMID: 25079928 Free PMC article. Clinical Trial.
Ocular Toxicity of Mitogen-Activated Protein Kinase Inhibitors.
Purbrick RMJ, Osunkunle OA, Talbot DC, Downes SM. Purbrick RMJ, et al. Among authors: downes sm. JAMA Oncol. 2017 Feb 1;3(2):275-277. doi: 10.1001/jamaoncol.2016.4213. JAMA Oncol. 2017. PMID: 27892980 No abstract available.
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia.
Xue K, Jolly JK, Barnard AR, Rudenko A, Salvetti AP, Patrício MI, Edwards TL, Groppe M, Orlans HO, Tolmachova T, Black GC, Webster AR, Lotery AJ, Holder GE, Downes SM, Seabra MC, MacLaren RE. Xue K, et al. Among authors: downes sm. Nat Med. 2018 Oct;24(10):1507-1512. doi: 10.1038/s41591-018-0185-5. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297895 Free PMC article.
Loss-of-Function Mutations in the CFH Gene Affecting Alternatively Encoded Factor H-like 1 Protein Cause Dominant Early-Onset Macular Drusen.
Taylor RL, Poulter JA, Downes SM, McKibbin M, Khan KN, Inglehearn CF, Webster AR, Hardcastle AJ, Michaelides M, Bishop PN, Clark SJ, Black GC; United Kingdom Inherited Retinal Dystrophy Consortium. Taylor RL, et al. Among authors: downes sm. Ophthalmology. 2019 Oct;126(10):1410-1421. doi: 10.1016/j.ophtha.2019.03.013. Epub 2019 Mar 21. Ophthalmology. 2019. PMID: 30905644 Free PMC article.
Impact of Diabetic Retinopathy on Sleep, Mood, and Quality of Life.
Morjaria R, Alexander I, Purbrick RMJ, Safa R, Chong NV, Wulff K, Foster RG, Downes SM; SOMNUS Study Group. Morjaria R, et al. Among authors: downes sm. Invest Ophthalmol Vis Sci. 2019 May 1;60(6):2304-2310. doi: 10.1167/iovs.18-26108. Invest Ophthalmol Vis Sci. 2019. PMID: 31117122 Free PMC article.
166 results