Doyle SL - Search Results

1

Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity.

Doyle SL, O'Neill LA. Doyle SL, et al. Biochem Pharmacol. 2006 Oct 30;72(9):1102-13. doi: 10.1016/j.bcp.2006.07.010. Epub 2006 Aug 22. Biochem Pharmacol. 2006. PMID: 16930560 Review.

2

Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide.

Doyle SL, Jefferies CA, O'Neill LA. Doyle SL, et al. J Biol Chem. 2005 Jun 24;280(25):23496-501. doi: 10.1074/jbc.C500053200. Epub 2005 Apr 22. J Biol Chem. 2005. PMID: 15849198 Free article.

3

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O'Neill LA. Gray P, et al. Among authors: doyle sl. J Biol Chem. 2006 Apr 14;281(15):10489-95. doi: 10.1074/jbc.M508892200. Epub 2006 Jan 26. J Biol Chem. 2006. PMID: 16439361 Free article.

4

Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.

Doyle SL, Jefferies CA, Feighery C, O'Neill LA. Doyle SL, et al. J Biol Chem. 2007 Dec 21;282(51):36953-60. doi: 10.1074/jbc.M707682200. Epub 2007 Oct 11. J Biol Chem. 2007. PMID: 17932028 Free article.

5

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

O'Neill LA, Bryant CE, Doyle SL. O'Neill LA, et al. Among authors: doyle sl. Pharmacol Rev. 2009 Jun;61(2):177-97. doi: 10.1124/pr.109.001073. Epub 2009 May 27. Pharmacol Rev. 2009. PMID: 19474110 Free PMC article. Review.

6

IL-10 inhibits miR-155 induction by toll-like receptors.

McCoy CE, Sheedy FJ, Qualls JE, Doyle SL, Quinn SR, Murray PJ, O'Neill LA. McCoy CE, et al. Among authors: doyle sl. J Biol Chem. 2010 Jul 2;285(27):20492-8. doi: 10.1074/jbc.M110.102111. Epub 2010 Apr 30. J Biol Chem. 2010. PMID: 20435894 Free PMC article.

7

Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.

Jefferies CA, Doyle S, Brunner C, Dunne A, Brint E, Wietek C, Walch E, Wirth T, O'Neill LA. Jefferies CA, et al. J Biol Chem. 2003 Jul 11;278(28):26258-64. doi: 10.1074/jbc.M301484200. Epub 2003 Apr 30. J Biol Chem. 2003. PMID: 12724322 Free article.

8

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation.

Mansell A, Smith R, Doyle SL, Gray P, Fenner JE, Crack PJ, Nicholson SE, Hilton DJ, O'Neill LA, Hertzog PJ. Mansell A, et al. Among authors: doyle sl. Nat Immunol. 2006 Feb;7(2):148-55. doi: 10.1038/ni1299. Epub 2006 Jan 15. Nat Immunol. 2006. PMID: 16415872

9

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.

Palsson-McDermott EM, Doyle SL, McGettrick AF, Hardy M, Husebye H, Banahan K, Gong M, Golenbock D, Espevik T, O'Neill LA. Palsson-McDermott EM, et al. Among authors: doyle sl. Nat Immunol. 2009 Jun;10(6):579-86. doi: 10.1038/ni.1727. Epub 2009 May 3. Nat Immunol. 2009. PMID: 19412184

10

The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.

Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF. Doyle SL, et al. Nat Commun. 2012 Feb 28;3:707. doi: 10.1038/ncomms1706. Nat Commun. 2012. PMID: 22426228 Free article.

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