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A highly efficacious live attenuated mumps virus-based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike.
Zhang Y, Lu M, Mahesh KC, Kim E, Shamseldin MM, Ye C, Dravid P, Chamblee M, Park JG, Hall JM, Trivedi S, Chaiwatpongsakorn S, Kenny AD, Murthy SS, Sharma H, Liang X, Yount JS, Kapoor A, Martinez-Sobrido L, Dubey P, Boyaka PN, Peeples ME, Li J. Zhang Y, et al. Among authors: dravid p. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2201616119. doi: 10.1073/pnas.2201616119. Epub 2022 Jul 27. Proc Natl Acad Sci U S A. 2022. PMID: 35895717 Free PMC article.
A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike.
Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. Lu M, et al. Among authors: dravid p. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2026153118. doi: 10.1073/pnas.2026153118. Proc Natl Acad Sci U S A. 2021. PMID: 33688034 Free PMC article.
A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters.
Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. Lu M, et al. Among authors: dravid p. J Virol. 2021 Sep 27;95(20):e0059221. doi: 10.1128/JVI.00592-21. Epub 2021 Aug 11. J Virol. 2021. PMID: 34379509 Free PMC article.
Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission.
Ye C, Park JG, Chiem K, Dravid P, Allué-Guardia A, Garcia-Vilanova A, Kapoor A, Walter MR, Kobie JJ, Plemper RK, Torrelles JB, Martinez-Sobrido L. Ye C, et al. Among authors: dravid p. bioRxiv [Preprint]. 2022 Mar 14:2022.03.13.484172. doi: 10.1101/2022.03.13.484172. bioRxiv. 2022. PMID: 35313573 Free PMC article. Updated. Preprint.
SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern.
Lu M, Chamblee M, Zhang Y, Ye C, Dravid P, Park JG, Mahesh KC, Trivedi S, Murthy S, Sharma H, Cassady C, Chaiwatpongsakorn S, Liang X, Yount JS, Boyaka PN, Peeples ME, Martinez-Sobrido L, Kapoor A, Li J. Lu M, et al. Among authors: dravid p. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2110105119. doi: 10.1073/pnas.2110105119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994646 Free PMC article.
Immunization with Recombinant Accessory Protein-Deficient SARS-CoV-2 Protects against Lethal Challenge and Viral Transmission.
Ye C, Park JG, Chiem K, Dravid P, Allué-Guardia A, Garcia-Vilanova A, Pino Tamayo P, Shivanna V, Kapoor A, Walter MR, Kobie JJ, Plemper RK, Torrelles JB, Martinez-Sobrido L. Ye C, et al. Among authors: dravid p. Microbiol Spectr. 2023 Jun 15;11(3):e0065323. doi: 10.1128/spectrum.00653-23. Epub 2023 May 16. Microbiol Spectr. 2023. PMID: 37191507 Free PMC article.
24 results