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Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
Saraon P, Snider J, Schormann W, Rai A, Radulovich N, Sánchez-Osuna M, Coulombe-Huntington J, Huard C, Mohammed M, Lima-Fernandes E, Thériault B, Halabelian L, Chan M, Joshi D, Drecun L, Yao Z, Pathmanathan S, Wong V, Lyakisheva A, Aboualizadeh F, Niu L, Li F, Kiyota T, Subramanian R, Joseph B, Aman A, Prakesch M, Isaac M, Mamai A, Poda G, Vedadi M, Marcellus R, Uehling D, Leighl N, Sacher A, Samaržija M, Jakopović M, Arrowsmith C, Tyers M, Tsao MS, Andrews D, Al-Awar R, Stagljar I. Saraon P, et al. Among authors: drecun l. J Mol Biol. 2021 Nov 19;433(23):167294. doi: 10.1016/j.jmb.2021.167294. Epub 2021 Oct 16. J Mol Biol. 2021. PMID: 34662547
A Comprehensive Membrane Interactome Mapping of Sho1p Reveals Fps1p as a Novel Key Player in the Regulation of the HOG Pathway in S. cerevisiae.
Lam MH, Snider J, Rehal M, Wong V, Aboualizadeh F, Drecun L, Wong O, Jubran B, Li M, Ali M, Jessulat M, Deineko V, Miller R, Lee Me, Park HO, Davidson A, Babu M, Stagljar I. Lam MH, et al. Among authors: drecun l. J Mol Biol. 2015 Jun 5;427(11):2088-103. doi: 10.1016/j.jmb.2015.01.016. Epub 2015 Jan 30. J Mol Biol. 2015. PMID: 25644660 Free PMC article.
A drug discovery platform to identify compounds that inhibit EGFR triple mutants.
Saraon P, Snider J, Kalaidzidis Y, Wybenga-Groot LE, Weiss K, Rai A, Radulovich N, Drecun L, Vučković N, Vučetić A, Wong V, Thériault B, Pham NA, Park JH, Datti A, Wang J, Pathmanathan S, Aboualizadeh F, Lyakisheva A, Yao Z, Wang Y, Joseph B, Aman A, Moran MF, Prakesch M, Poda G, Marcellus R, Uehling D, Samaržija M, Jakopović M, Tsao MS, Shepherd FA, Sacher A, Leighl N, Akhmanova A, Al-Awar R, Zerial M, Stagljar I. Saraon P, et al. Among authors: drecun l. Nat Chem Biol. 2020 May;16(5):577-586. doi: 10.1038/s41589-020-0484-2. Epub 2020 Feb 24. Nat Chem Biol. 2020. PMID: 32094923 Free PMC article.
A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies.
Yao Z, Drecun L, Aboualizadeh F, Kim SJ, Li Z, Wood H, Valcourt EJ, Manguiat K, Plenderleith S, Yip L, Li X, Zhong Z, Yue FY, Closas T, Snider J, Tomic J, Drews SJ, Drebot MA, McGeer A, Ostrowski M, Mubareka S, Rini JM, Owen S, Stagljar I. Yao Z, et al. Among authors: drecun l. Nat Commun. 2021 Mar 22;12(1):1806. doi: 10.1038/s41467-021-22102-6. Nat Commun. 2021. PMID: 33753733 Free PMC article.