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Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.
Assay Drug Dev Technol. 2010 Aug;8(4):437-58. doi: 10.1089/adt.2010.0281.
Assay Drug Dev Technol. 2010.
PMID: 20662736
Free PMC article.
Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.
Dudgeon DD, Shinde S, Hua Y, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA.
Dudgeon DD, et al.
J Biomol Screen. 2010 Aug;15(7):766-82. doi: 10.1177/1087057110375304. Epub 2010 Jul 16.
J Biomol Screen. 2010.
PMID: 20639499
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The substrate recognition domains of the N-end rule pathway.
Tasaki T, Zakrzewska A, Dudgeon DD, Jiang Y, Lazo JS, Kwon YT.
Tasaki T, et al. Among authors: dudgeon dd.
J Biol Chem. 2009 Jan 16;284(3):1884-95. doi: 10.1074/jbc.M803641200. Epub 2008 Nov 13.
J Biol Chem. 2009.
PMID: 19008229
Free PMC article.
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Optimization of ultrasound contrast agents with computational models to improve selection of ligands and binding strength.
Maul TM, Dudgeon DD, Beste MT, Hammer DA, Lazo JS, Villanueva FS, Wagner WR.
Maul TM, et al. Among authors: dudgeon dd.
Biotechnol Bioeng. 2010 Dec 1;107(5):854-64. doi: 10.1002/bit.22857.
Biotechnol Bioeng. 2010.
PMID: 20665479
Free PMC article.
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New regulators of a high affinity Ca2+ influx system revealed through a genome-wide screen in yeast.
Martin DC, Kim H, Mackin NA, Maldonado-Báez L, Evangelista CC Jr, Beaudry VG, Dudgeon DD, Naiman DQ, Erdman SE, Cunningham KW.
Martin DC, et al. Among authors: dudgeon dd.
J Biol Chem. 2011 Mar 25;286(12):10744-54. doi: 10.1074/jbc.M110.177451. Epub 2011 Jan 20.
J Biol Chem. 2011.
PMID: 21252230
Free PMC article.
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Multiple signaling pathways regulate yeast cell death during the response to mating pheromones.
Zhang NN, Dudgeon DD, Paliwal S, Levchenko A, Grote E, Cunningham KW.
Zhang NN, et al. Among authors: dudgeon dd.
Mol Biol Cell. 2006 Aug;17(8):3409-22. doi: 10.1091/mbc.e06-03-0177. Epub 2006 May 31.
Mol Biol Cell. 2006.
PMID: 16738305
Free PMC article.
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Nonapoptotic death of Saccharomyces cerevisiae cells that is stimulated by Hsp90 and inhibited by calcineurin and Cmk2 in response to endoplasmic reticulum stresses.
Dudgeon DD, Zhang N, Ositelu OO, Kim H, Cunningham KW.
Dudgeon DD, et al.
Eukaryot Cell. 2008 Dec;7(12):2037-51. doi: 10.1128/EC.00291-08. Epub 2008 Sep 19.
Eukaryot Cell. 2008.
PMID: 18806210
Free PMC article.
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