Duncan JA - Search Results

1

Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome.

Kebaier C, Chamberland RR, Allen IC, Gao X, Broglie PM, Hall JD, Jania C, Doerschuk CM, Tilley SL, Duncan JA. Kebaier C, et al. Among authors: duncan ja. J Infect Dis. 2012 Mar 1;205(5):807-17. doi: 10.1093/infdis/jir846. Epub 2012 Jan 25. J Infect Dis. 2012. PMID: 22279123 Free PMC article.

2

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.

Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Duncan JA, et al. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8041-6. doi: 10.1073/pnas.0611496104. Epub 2007 May 2. Proc Natl Acad Sci U S A. 2007. PMID: 17483456 Free PMC article.

3

Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death.

McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, Marriott I. McCall SH, et al. Among authors: duncan ja. J Bone Miner Res. 2008 Jan;23(1):30-40. doi: 10.1359/jbmr.071002. J Bone Miner Res. 2008. PMID: 17907925 Free PMC article.

4

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Willingham SB, et al. Among authors: duncan ja. Cell Host Microbe. 2007 Sep 13;2(3):147-59. doi: 10.1016/j.chom.2007.07.009. Cell Host Microbe. 2007. PMID: 18005730 Free PMC article.

5

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Duncan JA, et al. J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696. J Immunol. 2009. PMID: 19414800 Free PMC article.

6

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. Willingham SB, et al. Among authors: duncan ja. J Immunol. 2009 Aug 1;183(3):2008-15. doi: 10.4049/jimmunol.0900138. Epub 2009 Jul 8. J Immunol. 2009. PMID: 19587006 Free PMC article.

7

Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells.

Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. Craven RR, et al. Among authors: duncan ja. PLoS One. 2009 Oct 14;4(10):e7446. doi: 10.1371/journal.pone.0007446. PLoS One. 2009. PMID: 19826485 Free PMC article.

8

Cutting edge: NLRC5-dependent activation of the inflammasome.

Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Davis BK, et al. Among authors: duncan ja. J Immunol. 2011 Feb 1;186(3):1333-7. doi: 10.4049/jimmunol.1003111. Epub 2010 Dec 29. J Immunol. 2011. PMID: 21191067 Free PMC article.

9

Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis.

Taxman DJ, Swanson KV, Broglie PM, Wen H, Holley-Guthrie E, Huang MT, Callaway JB, Eitas TK, Duncan JA, Ting JP. Taxman DJ, et al. Among authors: duncan ja. J Biol Chem. 2012 Sep 21;287(39):32791-9. doi: 10.1074/jbc.M112.401737. Epub 2012 Jul 26. J Biol Chem. 2012. PMID: 22843689 Free PMC article.

10

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome.

Holzinger D, Gieldon L, Mysore V, Nippe N, Taxman DJ, Duncan JA, Broglie PM, Marketon K, Austermann J, Vogl T, Foell D, Niemann S, Peters G, Roth J, Löffler B. Holzinger D, et al. Among authors: duncan ja. J Leukoc Biol. 2012 Nov;92(5):1069-81. doi: 10.1189/jlb.0112014. Epub 2012 Aug 14. J Leukoc Biol. 2012. PMID: 22892107 Free PMC article.

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