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Year Number of Results
1999 1
2003 1
2005 2
2006 1
2008 1
2009 2
2010 1
2012 2
2013 1
2015 1
2016 1
2017 1
2018 3
2019 1
2020 1
2021 1
2022 1
2023 2
2024 1

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25 results

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Page 1
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.
Durant ST, Zheng L, Wang Y, Chen K, Zhang L, Zhang T, Yang Z, Riches L, Trinidad AG, Fok JHL, Hunt T, Pike KG, Wilson J, Smith A, Colclough N, Reddy VP, Sykes A, Janefeldt A, Johnström P, Varnäs K, Takano A, Ling S, Orme J, Stott J, Roberts C, Barrett I, Jones G, Roudier M, Pierce A, Allen J, Kahn J, Sule A, Karlin J, Cronin A, Chapman M, Valerie K, Illingworth R, Pass M. Durant ST, et al. Sci Adv. 2018 Jun 20;4(6):eaat1719. doi: 10.1126/sciadv.aat1719. eCollection 2018 Jun. Sci Adv. 2018. PMID: 29938225 Free PMC article.
ATM-Inhibitor AZD1390 Is a Radiosensitizer for Breast Cancer CNS Metastasis.
Tew BY, Kalfa AJ, Yang Z, Hurth KM, Simon T, Abnoosian E, Durant ST, Hamerlik P, Salhia B. Tew BY, et al. Among authors: durant st. Clin Cancer Res. 2023 Nov 1;29(21):4492-4503. doi: 10.1158/1078-0432.CCR-23-0290. Clin Cancer Res. 2023. PMID: 37585496 Free PMC article.
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease.
Tebay LE, Robertson H, Durant ST, Vitale SR, Penning TM, Dinkova-Kostova AT, Hayes JD. Tebay LE, et al. Among authors: durant st. Free Radic Biol Med. 2015 Nov;88(Pt B):108-146. doi: 10.1016/j.freeradbiomed.2015.06.021. Epub 2015 Jun 27. Free Radic Biol Med. 2015. PMID: 26122708 Free PMC article. Review.
p53 methylation--the Arg-ument is clear.
Durant ST, Cho EC, La Thangue NB. Durant ST, et al. Cell Cycle. 2009 Mar 15;8(6):801-2. doi: 10.4161/cc.8.6.7850. Epub 2009 Mar 14. Cell Cycle. 2009. PMID: 19221494
Arginine methylation regulates the p53 response.
Jansson M, Durant ST, Cho EC, Sheahan S, Edelmann M, Kessler B, La Thangue NB. Jansson M, et al. Among authors: durant st. Nat Cell Biol. 2008 Dec;10(12):1431-9. doi: 10.1038/ncb1802. Epub 2008 Nov 16. Nat Cell Biol. 2008. PMID: 19011621
ALT neuroblastoma chemoresistance due to telomere dysfunction-induced ATM activation is reversible with ATM inhibitor AZD0156.
Koneru B, Farooqi A, Nguyen TH, Chen WH, Hindle A, Eslinger C, Makena MR, Burrow TA, Wilson J, Smith A, Pilla Reddy V, Cadogan E, Durant ST, Reynolds CP. Koneru B, et al. Among authors: durant st. Sci Transl Med. 2021 Aug 18;13(607):eabd5750. doi: 10.1126/scitranslmed.abd5750. Sci Transl Med. 2021. PMID: 34408079 Free PMC article.
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment JV, Jackson SP. Balmus G, et al. Among authors: durant st. Nat Commun. 2019 Jan 8;10(1):87. doi: 10.1038/s41467-018-07729-2. Nat Commun. 2019. PMID: 30622252 Free PMC article.
25 results