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Year Number of Results
2013 2
2014 2
2015 2
2016 4
2018 2
2019 5
2020 1
2021 1
2023 3
2024 0

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Page 1
A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.
Kumthekar P, Ko CH, Paunesku T, Dixit K, Sonabend AM, Bloch O, Tate M, Schwartz M, Zuckerman L, Lezon R, Lukas RV, Jovanovic B, McCortney K, Colman H, Chen S, Lai B, Antipova O, Deng J, Li L, Tommasini-Ghelfi S, Hurley LA, Unruh D, Sharma NV, Kandpal M, Kouri FM, Davuluri RV, Brat DJ, Muzzio M, Glass M, Vijayakumar V, Heidel J, Giles FJ, Adams AK, James CD, Woloschak GE, Horbinski C, Stegh AH. Kumthekar P, et al. Among authors: unruh d. Sci Transl Med. 2021 Mar 10;13(584):eabb3945. doi: 10.1126/scitranslmed.abb3945. Sci Transl Med. 2021. PMID: 33692132 Free PMC article. Clinical Trial.
Postoperative risk of IDH-mutant glioma-associated seizures and their potential management with IDH-mutant inhibitors.
Drumm MR, Wang W, Sears TK, Bell-Burdett K, Javier R, Cotton KY, Webb B, Byrne K, Unruh D, Thirunavu V, Walshon J, Steffens A, McCortney K, Lukas RV, Phillips JJ, Mohamed E, Finan JD, Santana-Santos L, Heimberger AB, Franz CK, Kurz J, Templer JW, Swanson GT, Horbinski C. Drumm MR, et al. Among authors: unruh d. J Clin Invest. 2023 Jun 15;133(12):e168035. doi: 10.1172/JCI168035. J Clin Invest. 2023. PMID: 37104042 Free PMC article.
Determining venous thromboembolism risk in patients with adult-type diffuse glioma.
Burdett KB, Unruh D, Drumm M, Steffens A, Lamano J, Judkins J, Schwartz M, Javier R, Amidei C, Lipp ES, Peters KB, Lai A, Eldred BSC, Heimberger AB, McCortney K, Scholtens DM, Horbinski C. Burdett KB, et al. Among authors: unruh d. Blood. 2023 Mar 16;141(11):1322-1336. doi: 10.1182/blood.2022017858. Blood. 2023. PMID: 36399711 Free PMC article.
Mutant IDH1 and thrombosis in gliomas.
Unruh D, Schwarze SR, Khoury L, Thomas C, Wu M, Chen L, Chen R, Liu Y, Schwartz MA, Amidei C, Kumthekar P, Benjamin CG, Song K, Dawson C, Rispoli JM, Fatterpekar G, Golfinos JG, Kondziolka D, Karajannis M, Pacione D, Zagzag D, McIntyre T, Snuderl M, Horbinski C. Unruh D, et al. Acta Neuropathol. 2016 Dec;132(6):917-930. doi: 10.1007/s00401-016-1620-7. Epub 2016 Sep 23. Acta Neuropathol. 2016. PMID: 27664011 Free PMC article.
Docetaxel targets aggressive methylation profiles and serves as a radiosensitizer in high-risk meningiomas.
Youngblood MW, Tran AN, Wang W, An S, Scholtens D, Zhang L, O'Shea K, Pokorny JL, Magill ST, Sachdev S, Lukas RV, Ahmed A, Unruh D, Walshon J, McCortney K, Wang Y, Baran A, Sahm F, Aldape K, Chandler JP, David James C, Heimberger AB, Horbinski C. Youngblood MW, et al. Among authors: unruh d. Neuro Oncol. 2023 Mar 14;25(3):508-519. doi: 10.1093/neuonc/noac206. Neuro Oncol. 2023. PMID: 35976058 Free PMC article.
Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma.
Katagi H, Louis N, Unruh D, Sasaki T, He X, Zhang A, Ma Q, Piunti A, Shimazu Y, Lamano JB, Carcaboso AM, Tian X, Seluanov A, Gorbunova V, Laurie KL, Kondo A, Wadhwani NR, Lulla R, Goldman S, Venneti S, Becher OJ, Zou L, Shilatifard A, Hashizume R. Katagi H, et al. Among authors: unruh d. Clin Cancer Res. 2019 Sep 15;25(18):5572-5583. doi: 10.1158/1078-0432.CCR-18-3890. Epub 2019 Jun 21. Clin Cancer Res. 2019. PMID: 31227500 Free PMC article.
Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth.
Lamano JB, Lamano JB, Li YD, DiDomenico JD, Choy W, Veliceasa D, Oyon DE, Fakurnejad S, Ampie L, Kesavabhotla K, Kaur R, Kaur G, Biyashev D, Unruh DJ, Horbinski CM, James CD, Parsa AT, Bloch O. Lamano JB, et al. Among authors: unruh dj. Clin Cancer Res. 2019 Jun 15;25(12):3643-3657. doi: 10.1158/1078-0432.CCR-18-2402. Epub 2019 Mar 1. Clin Cancer Res. 2019. PMID: 30824583 Free PMC article.
20 results