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PBRM1 Regulates Stress Response in Epithelial Cells.
Porter EG, Dhiman A, Chowdhury B, Carter BC, Lin H, Stewart JC, Kazemian M, Wendt MK, Dykhuizen EC. Porter EG, et al. Among authors: dykhuizen ec. iScience. 2019 May 31;15:196-210. doi: 10.1016/j.isci.2019.04.027. Epub 2019 Apr 26. iScience. 2019. PMID: 31077944 Free PMC article.
Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma.
Carcamo S, Nguyen CB, Grossi E, Filipescu D, Alpsoy A, Dhiman A, Sun D, Narang S, Imig J, Martin TC, Parsons R, Aifantis I, Tsirigos A, Aguirre-Ghiso JA, Dykhuizen EC, Hasson D, Bernstein E. Carcamo S, et al. Among authors: dykhuizen ec. Cell Rep. 2022 Apr 5;39(1):110637. doi: 10.1016/j.celrep.2022.110637. Cell Rep. 2022. PMID: 35385731 Free PMC article.
Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening.
Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC. Shishodia S, et al. Among authors: dykhuizen ec. J Med Chem. 2022 Oct 27;65(20):13714-13735. doi: 10.1021/acs.jmedchem.2c00864. Epub 2022 Oct 13. J Med Chem. 2022. PMID: 36227159 Free PMC article.
PBRM1 bromodomains associate with RNA to facilitate chromatin association.
De Silva SM, Dhiman A, Sood S, Mercedes KF, Simmons WJ, Henen MA, Vögeli B, Dykhuizen EC, Musselman CA. De Silva SM, et al. Among authors: dykhuizen ec. Nucleic Acids Res. 2023 May 8;51(8):3631-3649. doi: 10.1093/nar/gkad072. Nucleic Acids Res. 2023. PMID: 36808431 Free PMC article.
38 results