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Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.
Ma S, Zhang B, LaFave LM, Earl AS, Chiang Z, Hu Y, Ding J, Brack A, Kartha VK, Tay T, Law T, Lareau C, Hsu YC, Regev A, Buenrostro JD. Ma S, et al. Among authors: earl as. Cell. 2020 Nov 12;183(4):1103-1116.e20. doi: 10.1016/j.cell.2020.09.056. Epub 2020 Oct 23. Cell. 2020. PMID: 33098772 Free PMC article.
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues.
Zhao T, Chiang ZD, Morriss JW, LaFave LM, Murray EM, Del Priore I, Meli K, Lareau CA, Nadaf NM, Li J, Earl AS, Macosko EZ, Jacks T, Buenrostro JD, Chen F. Zhao T, et al. Among authors: earl as. Nature. 2022 Jan;601(7891):85-91. doi: 10.1038/s41586-021-04217-4. Epub 2021 Dec 15. Nature. 2022. PMID: 34912115 Free PMC article.
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements.
Hu Y, Ma S, Kartha VK, Duarte FM, Horlbeck M, Zhang R, Shrestha R, Labade A, Kletzien H, Meliki A, Castillo A, Durand N, Mattei E, Anderson LJ, Tay T, Earl AS, Shoresh N, Epstein CB, Wagers A, Buenrostro JD. Hu Y, et al. Among authors: earl as. bioRxiv [Preprint]. 2023 Mar 29:2023.03.28.533945. doi: 10.1101/2023.03.28.533945. bioRxiv. 2023. PMID: 37034577 Free PMC article. Preprint.
In situ genome sequencing resolves DNA sequence and structure in intact biological samples.
Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F. Payne AC, et al. Among authors: earl as. Science. 2021 Feb 26;371(6532):eaay3446. doi: 10.1126/science.aay3446. Epub 2020 Dec 31. Science. 2021. PMID: 33384301 Free PMC article.