Edwards RM - Search Results

1

BB-10010: an active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties.

Hunter MG, Bawden L, Brotherton D, Craig S, Cribbes S, Czaplewski LG, Dexter TM, Drummond AH, Gearing AH, Heyworth CM, Lord BI, McCourt M, Varley PG, Wood LM, Edwards RM, Lewis PJ. Hunter MG, et al. Among authors: edwards rm. Blood. 1995 Dec 15;86(12):4400-8. Blood. 1995. PMID: 8541527 Free article.

2

Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants.

Czaplewski LG, McKeating J, Craven CJ, Higgins LD, Appay V, Brown A, Dudgeon T, Howard LA, Meyers T, Owen J, Palan SR, Tan P, Wilson G, Woods NR, Heyworth CM, Lord BI, Brotherton D, Christison R, Craig S, Cribbes S, Edwards RM, Evans SJ, Gilbert R, Morgan P, Randle E, Schofield N, Varley PG, Fisher J, Waltho JP, Hunter MG. Czaplewski LG, et al. Among authors: edwards rm. J Biol Chem. 1999 Jun 4;274(23):16077-84. doi: 10.1074/jbc.274.23.16077. J Biol Chem. 1999. PMID: 10347159 Free article.

3

Mobilization of early hematopoietic progenitor cells with BB-10010: a genetically engineered variant of human macrophage inflammatory protein-1 alpha.

Lord BI, Woolford LB, Wood LM, Czaplewski LG, McCourt M, Hunter MG, Edwards RM. Lord BI, et al. Among authors: edwards rm. Blood. 1995 Jun 15;85(12):3412-5. Blood. 1995. PMID: 7540061 Free article.

4

Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity.

Cook AL, Kirwin PM, Craig S, Bawden LJ, Green DR, Price MJ, Richardson SJ, Fallon A, Drummond AH, Edwards RM, et al. Cook AL, et al. Among authors: edwards rm. Biochem J. 1992 Jan 1;281 ( Pt 1)(Pt 1):57-65. doi: 10.1042/bj2810057. Biochem J. 1992. PMID: 1731768 Free PMC article.

5

Two PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation.

Clements JM, Bawden LJ, Bloxidge RE, Catlin G, Cook AL, Craig S, Drummond AH, Edwards RM, Fallon A, Green DR, et al. Clements JM, et al. Among authors: edwards rm. EMBO J. 1991 Dec;10(13):4113-20. doi: 10.1002/j.1460-2075.1991.tb04988.x. EMBO J. 1991. PMID: 1661670 Free PMC article.

6

Plasminogen mutants activated by thrombin. Potential thrombus-selective thrombolytic agents.

Dawson KM, Cook A, Devine JM, Edwards RM, Hunter MG, Raper RH, Roberts G. Dawson KM, et al. Among authors: edwards rm. J Biol Chem. 1994 Jun 10;269(23):15989-92. J Biol Chem. 1994. PMID: 8206894 Free article.

7

Alpha4 integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity.

Newham P, Craig SE, Seddon GN, Schofield NR, Rees A, Edwards RM, Jones EY, Humphries MJ. Newham P, et al. Among authors: edwards rm. J Biol Chem. 1997 Aug 1;272(31):19429-40. doi: 10.1074/jbc.272.31.19429. J Biol Chem. 1997. PMID: 9235944 Free article.

8

Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin.

Clements JM, Newham P, Shepherd M, Gilbert R, Dudgeon TJ, Needham LA, Edwards RM, Berry L, Brass A, Humphries MJ. Clements JM, et al. Among authors: edwards rm. J Cell Sci. 1994 Aug;107 ( Pt 8):2127-35. doi: 10.1242/jcs.107.8.2127. J Cell Sci. 1994. PMID: 7527054

9

Structure-function relationships in human epidermal growth factor studied by site-directed mutagenesis and 1H NMR.

Hommel U, Dudgeon TJ, Fallon A, Edwards RM, Campbell ID. Hommel U, et al. Among authors: edwards rm. Biochemistry. 1991 Sep 10;30(36):8891-8. doi: 10.1021/bi00100a024. Biochemistry. 1991. PMID: 1909576

10

Structure-function analysis of epidermal growth factor: site directed mutagenesis and nuclear magnetic resonance.

Dudgeon TJ, Cooke RM, Baron M, Campbell ID, Edwards RM, Fallon A. Dudgeon TJ, et al. Among authors: edwards rm. FEBS Lett. 1990 Feb 26;261(2):392-6. doi: 10.1016/0014-5793(90)80600-n. FEBS Lett. 1990. PMID: 2178977 Free article.

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