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Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming.
Oger F, Moreno M, Derhourhi M, Thiroux B, Berberian L, Bourouh C, Durand E, Amanzougarene S, Badreddine A, Blanc E, Molendi-Coste O, Pineau L, Pasquetti G, Rolland L, Carney C, Bornaque F, Courty E, Gheeraert C, Eeckhoute J, Dombrowicz D, Kerr-Conte J, Pattou F, Staels B, Froguel P, Bonnefond A, Annicotte JS. Oger F, et al. Among authors: eeckhoute j. iScience. 2023 Jun 30;26(7):107231. doi: 10.1016/j.isci.2023.107231. eCollection 2023 Jul 21. iScience. 2023. PMID: 37496675 Free PMC article.
The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells.
Briand O, Helleboid-Chapman A, Ploton M, Hennuyer N, Carpentier R, Pattou F, Vandewalle B, Moerman E, Gmyr V, Kerr-Conte J, Eeckhoute J, Staels B, Lefebvre P. Briand O, et al. Among authors: eeckhoute j. Mol Endocrinol. 2012 Mar;26(3):399-413. doi: 10.1210/me.2011-1317. Epub 2012 Feb 2. Mol Endocrinol. 2012. PMID: 22301783 Free PMC article.
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers.
Sérandour AA, Avner S, Oger F, Bizot M, Percevault F, Lucchetti-Miganeh C, Palierne G, Gheeraert C, Barloy-Hubler F, Péron CL, Madigou T, Durand E, Froguel P, Staels B, Lefebvre P, Métivier R, Eeckhoute J, Salbert G. Sérandour AA, et al. Among authors: eeckhoute j. Nucleic Acids Res. 2012 Sep 1;40(17):8255-65. doi: 10.1093/nar/gks595. Epub 2012 Jun 22. Nucleic Acids Res. 2012. PMID: 22730288 Free PMC article.
Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes.
Oger F, Dubois-Chevalier J, Gheeraert C, Avner S, Durand E, Froguel P, Salbert G, Staels B, Lefebvre P, Eeckhoute J. Oger F, et al. Among authors: eeckhoute j. J Biol Chem. 2014 Jan 10;289(2):708-22. doi: 10.1074/jbc.M113.526996. Epub 2013 Nov 27. J Biol Chem. 2014. PMID: 24288131 Free PMC article.
Cell-specific dysregulation of microRNA expression in obese white adipose tissue.
Oger F, Gheeraert C, Mogilenko D, Benomar Y, Molendi-Coste O, Bouchaert E, Caron S, Dombrowicz D, Pattou F, Duez H, Eeckhoute J, Staels B, Lefebvre P. Oger F, et al. Among authors: eeckhoute j. J Clin Endocrinol Metab. 2014 Aug;99(8):2821-33. doi: 10.1210/jc.2013-4259. Epub 2014 Apr 23. J Clin Endocrinol Metab. 2014. PMID: 24758184
76 results