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MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α.
Kovaleva V, Yu LY, Ivanova L, Shpironok O, Nam J, Eesmaa A, Kumpula EP, Sakson S, Toots U, Ustav M, Huiskonen JT, Voutilainen MH, Lindholm P, Karelson M, Saarma M. Kovaleva V, et al. Among authors: eesmaa a. Cell Rep. 2023 Feb 28;42(2):112066. doi: 10.1016/j.celrep.2023.112066. Epub 2023 Feb 3. Cell Rep. 2023. PMID: 36739529 Free article.
Neuroplastin Modulates Anti-inflammatory Effects of MANF.
Yagi T, Asada R, Kanekura K, Eesmaa A, Lindahl M, Saarma M, Urano F. Yagi T, et al. Among authors: eesmaa a. iScience. 2020 Nov 17;23(12):101810. doi: 10.1016/j.isci.2020.101810. eCollection 2020 Dec 18. iScience. 2020. PMID: 33299977 Free PMC article.
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo.
Albert K, Raymundo DP, Panhelainen A, Eesmaa A, Shvachiy L, Araújo GR, Chmielarz P, Yan X, Singh A, Cordeiro Y, Palhano FL, Foguel D, Luk KC, Domanskyi A, Voutilainen MH, Huttunen HJ, Outeiro TF, Saarma M, Almeida MS, Airavaara M. Albert K, et al. Among authors: eesmaa a. Mol Ther. 2021 Sep 1;29(9):2821-2840. doi: 10.1016/j.ymthe.2021.04.035. Epub 2021 May 1. Mol Ther. 2021. PMID: 33940158 Free PMC article.