Egebjerg J - Search Results

1

Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives.

Andersen TF, Tikhonov DB, Bølcho U, Bolshakov K, Nelson JK, Pluteanu F, Mellor IR, Egebjerg J, Strømgaard K. Andersen TF, et al. Among authors: egebjerg j. J Med Chem. 2006 Sep 7;49(18):5414-23. doi: 10.1021/jm060606j. J Med Chem. 2006. PMID: 16942015

2

A tetrazolyl-substituted subtype-selective AMPA receptor agonist.

Vogensen SB, Frydenvang K, Greenwood JR, Postorino G, Nielsen B, Pickering DS, Ebert B, Bølcho U, Egebjerg J, Gajhede M, Kastrup JS, Johansen TN, Clausen RP, Krogsgaard-Larsen P. Vogensen SB, et al. Among authors: egebjerg j. J Med Chem. 2007 May 17;50(10):2408-14. doi: 10.1021/jm061439q. Epub 2007 Apr 25. J Med Chem. 2007. PMID: 17455929

3

Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA.

Jensen AA, Christesen T, Bølcho U, Greenwood JR, Postorino G, Vogensen SB, Johansen TN, Egebjerg J, Bräuner-Osborne H, Clausen RP. Jensen AA, et al. Among authors: egebjerg j. J Med Chem. 2007 Aug 23;50(17):4177-85. doi: 10.1021/jm070532r. Epub 2007 Aug 2. J Med Chem. 2007. PMID: 17672447

4

Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors.

Kromann H, Krikstolaityte S, Andersen AJ, Andersen K, Krogsgaard-Larsen P, Jaroszewski JW, Egebjerg J, Strømgaard K. Kromann H, et al. Among authors: egebjerg j. J Med Chem. 2002 Dec 19;45(26):5745-54. doi: 10.1021/jm020314s. J Med Chem. 2002. PMID: 12477358

5

Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors.

Jensen LS, Bølcho U, Egebjerg J, Strømgaard K. Jensen LS, et al. Among authors: egebjerg j. ChemMedChem. 2006 Apr;1(4):419-28. doi: 10.1002/cmdc.200500093. ChemMedChem. 2006. PMID: 16892377

6

Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants.

Andersen J, Taboureau O, Hansen KB, Olsen L, Egebjerg J, Strømgaard K, Kristensen AS. Andersen J, et al. Among authors: egebjerg j. J Biol Chem. 2009 Apr 10;284(15):10276-84. doi: 10.1074/jbc.M806907200. Epub 2009 Feb 12. J Biol Chem. 2009. PMID: 19213730 Free PMC article.

7

Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter.

Andersen J, Olsen L, Hansen KB, Taboureau O, Jørgensen FS, Jørgensen AM, Bang-Andersen B, Egebjerg J, Strømgaard K, Kristensen AS. Andersen J, et al. Among authors: egebjerg j. J Biol Chem. 2010 Jan 15;285(3):2051-63. doi: 10.1074/jbc.M109.072587. Epub 2009 Nov 5. J Biol Chem. 2010. PMID: 19892699 Free PMC article.

8

Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.

Hogner A, Greenwood JR, Liljefors T, Lunn ML, Egebjerg J, Larsen IK, Gouaux E, Kastrup JS. Hogner A, et al. Among authors: egebjerg j. J Med Chem. 2003 Jan 16;46(2):214-21. doi: 10.1021/jm020989v. J Med Chem. 2003. PMID: 12519060

9

N-Hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands.

Clausen RP, Christensen C, Hansen KB, Greenwood JR, Jørgensen L, Micale N, Madsen JC, Nielsen B, Egebjerg J, Bräuner-Osborne H, Traynelis SF, Kristensen JL. Clausen RP, et al. Among authors: egebjerg j. J Med Chem. 2008 Jul 24;51(14):4179-87. doi: 10.1021/jm800025e. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578474 Free PMC article.

10

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.

Brehm L, Greenwood JR, Hansen KB, Nielsen B, Egebjerg J, Stensbøl TB, Bräuner-Osborne H, Sløk FA, Kronborg TT, Krogsgaard-Larsen P. Brehm L, et al. Among authors: egebjerg j. J Med Chem. 2003 Apr 10;46(8):1350-8. doi: 10.1021/jm0204441. J Med Chem. 2003. PMID: 12672235

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