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Page 1
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis.
Bülck C, Nyström EEL, Koudelka T, Mannbar-Frahm M, Andresen G, Radhouani M, Tran F, Scharfenberg F, Schrell F, Armbrust F, Dahlke E, Zhao B, Vervaeke A, Theilig F, Rosenstiel P, Starkl P, Rosshart SP, Fickenscher H, Tholey A, Hansson GC, Becker-Pauly C. Bülck C, et al. Among authors: dahlke e. Sci Adv. 2023 Mar 31;9(13):eadf4055. doi: 10.1126/sciadv.adf4055. Epub 2023 Mar 31. Sci Adv. 2023. PMID: 37000885 Free PMC article.
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney.
Rinschen MM, Harder JL, Carter-Timofte ME, Zanon Rodriguez L, Mirabelli C, Demir F, Kurmasheva N, Ramakrishnan SK, Kunke M, Tan Y, Billing A, Dahlke E, Larionov AA, Bechtel-Walz W, Aukschun U, Grabbe M, Nielsen R, Christensen EI, Kretzler M, Huber TB, Wobus CE, Olagnier D, Siuzdak G, Grahammer F, Theilig F. Rinschen MM, et al. Among authors: dahlke e. Sci Signal. 2022 Nov 29;15(762):eabo7940. doi: 10.1126/scisignal.abo7940. Epub 2022 Nov 29. Sci Signal. 2022. PMID: 36445937 Free PMC article.
Targeted deletion of von-Hippel-Lindau in the proximal tubule conditions the kidney against early diabetic kidney disease.
Kunke M, Knöfler H, Dahlke E, Zanon Rodriguez L, Böttner M, Larionov A, Saudenova M, Ohrenschall GM, Westermann M, Porubsky S, Bernardes JP, Häsler R, Magnin JL, Koepsell H, Jouret F, Theilig F. Kunke M, et al. Among authors: dahlke e. Cell Death Dis. 2023 Aug 26;14(8):562. doi: 10.1038/s41419-023-06074-7. Cell Death Dis. 2023. PMID: 37626062 Free PMC article.
Primidone blocks RIPK1-driven cell death and inflammation.
Riebeling T, Jamal K, Wilson R, Kolbrink B, von Samson-Himmelstjerna FA, Moerke C, Ramos Garcia L, Dahlke E, Michels F, Lühder F, Schunk D, Doldi P, Tyczynski B, Kribben A, Flüh C, Theilig F, Kunzendorf U, Meier P, Krautwald S. Riebeling T, et al. Among authors: dahlke e. Cell Death Differ. 2021 May;28(5):1610-1626. doi: 10.1038/s41418-020-00690-y. Epub 2020 Dec 3. Cell Death Differ. 2021. PMID: 33273695 Free PMC article.
Molecular signature of stem-like glioma cells (SLGCs) from human glioblastoma and gliosarcoma.
Zechel C, Loy M, Wegner C, Dahlke E, Soetje B, Baehr L, Leppert J, Ostermaier JJ, Lueg T, Nielsen J, Elßner J, Willeke V, Marzahl S, Tronnier V, Madany Mamlouk A. Zechel C, et al. Among authors: dahlke e. PLoS One. 2024 Feb 2;19(2):e0291368. doi: 10.1371/journal.pone.0291368. eCollection 2024. PLoS One. 2024. PMID: 38306361 Free PMC article.
A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.
Issler N, Afonso S, Weissman I, Jordan K, Cebrian-Serrano A, Meindl K, Dahlke E, Tziridis K, Yan G, Robles-López JM, Tabernero L, Patel V, Kesselheim A, Klootwijk ED, Stanescu HC, Dumitriu S, Iancu D, Tekman M, Mozere M, Jaureguiberry G, Outtandy P, Russell C, Forst AL, Sterner C, Heinl ES, Othmen H, Tegtmeier I, Reichold M, Schiessl IM, Limm K, Oefner P, Witzgall R, Fu L, Theilig F, Schilling A, Shuster Biton E, Kalfon L, Fedida A, Arnon-Sheleg E, Ben Izhak O, Magen D, Anikster Y, Schulze H, Ziegler C, Lowe M, Davies B, Böckenhauer D, Kleta R, Falik Zaccai TC, Warth R. Issler N, et al. Among authors: dahlke e. J Am Soc Nephrol. 2022 Apr;33(4):732-745. doi: 10.1681/ASN.2021101312. Epub 2022 Feb 11. J Am Soc Nephrol. 2022. PMID: 35149593 Free PMC article.
Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome.
Larionov A, Dahlke E, Kunke M, Zanon Rodriguez L, Schiessl IM, Magnin JL, Kern U, Alli AA, Mollet G, Schilling O, Castrop H, Theilig F. Larionov A, et al. Among authors: dahlke e. J Cell Mol Med. 2019 Oct;23(10):6543-6553. doi: 10.1111/jcmm.14387. Epub 2019 Jul 31. J Cell Mol Med. 2019. PMID: 31368174 Free PMC article.