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Page 1
Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science. 2022 Nov 4;378(6619):549-553. doi: 10.1126/science.add7574. Epub 2022 Nov 3.
Science. 2022.
PMID: 36378961
Free PMC article.
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Surka C, Jin L, Mbong N, Lu CC, Jang IS, Rychak E, Mendy D, Clayton T, Tindall E, Hsu C, Fontanillo C, Tran E, Contreras A, Ng SWK, Matyskiela M, Wang K, Chamberlain P, Cathers B, Carmichael J, Hansen J, Wang JCY, Minden MD, Fan J, Pierce DW, Pourdehnad M, Rolfe M, Lopez-Girona A, Dick JE, Lu G.
Surka C, et al. Among authors: tran e.
Blood. 2021 Feb 4;137(5):661-677. doi: 10.1182/blood.2020008676.
Blood. 2021.
PMID: 33197925
Free PMC article.
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Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex.
Matyskiela ME, Clayton T, Zheng X, Mayne C, Tran E, Carpenter A, Pagarigan B, McDonald J, Rolfe M, Hamann LG, Lu G, Chamberlain PP.
Matyskiela ME, et al. Among authors: tran e.
Nat Struct Mol Biol. 2020 Apr;27(4):319-322. doi: 10.1038/s41594-020-0405-9. Epub 2020 Apr 6.
Nat Struct Mol Biol. 2020.
PMID: 32251415
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Long noncoding RNA GATA2-AS1 augments endothelial hypoxia inducible factor 1-α induction and regulates hypoxic signaling.
Man HSJ, Subramaniam N, Downs T, Sukumar AN, Saha AD, Nair R, Chen L, Teitelbaum D, Turgeon PJ, Ku KH, Tran E, de Perrot M, Marsden PA.
Man HSJ, et al. Among authors: tran e.
J Biol Chem. 2023 May;299(5):103029. doi: 10.1016/j.jbc.2023.103029. Epub 2023 Feb 17.
J Biol Chem. 2023.
PMID: 36806681
Free PMC article.
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In Vivo Function of Flow-Responsive Cis-DNA Elements of eNOS Gene: A Role for Chromatin-Based Mechanisms.
Ku KH, Dubinsky MK, Sukumar AN, Subramaniam N, Feasson MYM, Nair R, Tran E, Steer BM, Knight BJ, Marsden PA.
Ku KH, et al. Among authors: tran e.
Circulation. 2021 Aug 3;144(5):365-381. doi: 10.1161/CIRCULATIONAHA.120.051078. Epub 2021 Apr 29.
Circulation. 2021.
PMID: 33910388
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Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Baltgalvis KA, Lamb KN, Symons KT, Wu CC, Hoffman MA, Snead AN, Song X, Glaza T, Kikuchi S, Green JC, Rogness DC, Lam B, Rodriguez-Aguirre ME, Woody DR, Eissler CL, Rodiles S, Negron SM, Bernard SM, Tran E, Pollock J, Tabatabaei A, Contreras V, Williams HN, Pastuszka MK, Sigler JJ, Pettazzoni P, Rudolph MG, Classen M, Brugger D, Claiborne C, Plancher JM, Cuartas I, Seoane J, Burgess LE, Abraham RT, Weinstein DS, Simon GM, Patricelli MP, Kinsella TM.
Baltgalvis KA, et al. Among authors: tran e.
Nature. 2024 Apr 24. doi: 10.1038/s41586-024-07318-y. Online ahead of print.
Nature. 2024.
PMID: 38658751
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