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Page 1
Impaired protein hydroxylase activity causes replication stress and developmental abnormalities in humans.
Fletcher SC, Hall C, Kennedy TJ, Pajusalu S, Wojcik MH, Boora U, Li C, Oja KT, Hendrix E, Westrip CA, Andrijes R, Piasecka SK, Singh M, El-Asrag ME, Ptasinska A, Tillmann V, Higgs MR, Carere DA, Beggs AD, Pappas J, Rabin R, Smerdon SJ, Stewart GS, Õunap K, Coleman ML. Fletcher SC, et al. Among authors: el asrag me. J Clin Invest. 2023 Apr 3;133(7):e152784. doi: 10.1172/JCI152784. J Clin Invest. 2023. PMID: 36795492 Free PMC article.
Derivation of a new model of lung adenocarcinoma using canine lung cancer organoids for translational research in pulmonary medicine.
Shiota Sato Y, Elbadawy M, Suzuki K, Tsunedomi R, Nagano H, Ishihara Y, Yamamoto H, Azakami D, Uchide T, Fukushima R, Tanaka R, Yoshida T, Mori T, Abugomaa A, Kaneda M, Yamawaki H, Shinohara Y, Aboubakr M, El-Asrag ME, Usui T, Sasaki K. Shiota Sato Y, et al. Among authors: el asrag me. Biomed Pharmacother. 2023 Sep;165:115079. doi: 10.1016/j.biopha.2023.115079. Epub 2023 Jul 4. Biomed Pharmacother. 2023. PMID: 37413906 Free article.
Late-Onset Autosomal Dominant Macular Degeneration Caused by Deletion of the CRX Gene.
Yahya S, Smith CEL, Poulter JA, McKibbin M, Arno G, Ellingford J, Kämpjärvi K, Khan MI, Cremers FPM, Hardcastle AJ, Castle B, Steel DHW, Webster AR, Black GC, El-Asrag ME, Ali M, Toomes C, Inglehearn CF; UK Inherited Retinal Dystrophy Consortium; Genomics England Research Consortium. Yahya S, et al. Among authors: el asrag me. Ophthalmology. 2023 Jan;130(1):68-76. doi: 10.1016/j.ophtha.2022.07.023. Epub 2022 Aug 5. Ophthalmology. 2023. PMID: 35934205 Free article.
Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer.
Wanigasooriya K, Barros-Silva JD, Tee L, El-Asrag ME, Stodolna A, Pickles OJ, Stockton J, Bryer C, Hoare R, Whalley CM, Tyler R, Sillo T, Yau C, Ismail T, Beggs AD. Wanigasooriya K, et al. Among authors: el asrag me. Front Oncol. 2022 Jul 4;12:920444. doi: 10.3389/fonc.2022.920444. eCollection 2022. Front Oncol. 2022. PMID: 35860583 Free PMC article.
PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies.
Al-Amri AH, Armstrong P, Amici M, Ligneul C, Rouse J, El-Asrag ME, Pantiru A, Vancollie VE, Ng HWY, Ogbeta JA, Goodchild K, Ellegood J, Lelliott CJ, Mullins JGL, Bretman A, Al-Ali R, Beetz C, Al-Gazali L, Al Shamsi A, Lerch JP, Mellor JR, Al Sayegh A, Ali M, Inglehearn CF, Clapcote SJ. Al-Amri AH, et al. Among authors: el asrag me. Biol Psychiatry. 2022 Aug 15;92(4):323-334. doi: 10.1016/j.biopsych.2021.12.017. Epub 2022 Jan 11. Biol Psychiatry. 2022. PMID: 35227461 Free PMC article.
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