El-Kattan Y - Search Results

1

BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.

Babu YS, Chand P, Bantia S, Kotian P, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Elliott AJ, Parker CD, Ananth SL, Horn LL, Laver GW, Montgomery JA. Babu YS, et al. J Med Chem. 2000 Sep 21;43(19):3482-6. doi: 10.1021/jm0002679. J Med Chem. 2000. PMID: 11000002 No abstract available.

2

Comparison of the anti-influenza virus activity of RWJ-270201 with those of oseltamivir and zanamivir.

Bantia S, Parker CD, Ananth SL, Horn LL, Andries K, Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin T, Hutchison TL, Montgomery JA, Kellog DL, Babu YS. Bantia S, et al. Antimicrob Agents Chemother. 2001 Apr;45(4):1162-7. doi: 10.1128/AAC.45.4.1162-1167.2001. Antimicrob Agents Chemother. 2001. PMID: 11257030 Free PMC article.

3

Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity.

Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Babu YS, Bantia S, Elliott AJ, Montgomery JA. Chand P, et al. J Med Chem. 2001 Dec 6;44(25):4379-92. doi: 10.1021/jm010277p. J Med Chem. 2001. PMID: 11728184

4

Syntheses and neuraminidase inhibitory activity of multisubstituted cyclopentane amide derivatives.

Chand P, Babu YS, Bantia S, Rowland S, Dehghani A, Kotian PL, Hutchison TL, Ali S, Brouillette W, El-Kattan Y, Lin TH. Chand P, et al. J Med Chem. 2004 Apr 8;47(8):1919-29. doi: 10.1021/jm0303406. J Med Chem. 2004. PMID: 15055992

5

Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo.

Chand P, Bantia S, Kotian PL, El-Kattan Y, Lin TH, Babu YS. Chand P, et al. Bioorg Med Chem. 2005 Jun 2;13(12):4071-7. doi: 10.1016/j.bmc.2005.03.048. Epub 2005 Apr 25. Bioorg Med Chem. 2005. PMID: 15911320

6

Synthesis of 9-[1-(substituted)-3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents.

Wu M, El-Kattan Y, Lin TH, Ghosh A, Vadlakonda S, Kotian PL, Babu YS, Chand P. Wu M, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1543-68. doi: 10.1080/15257770500268673. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438034

7

Synthesis of 9-[1-(substituted)-2-(phosphonomethoxy)ethyl]adenine derivatives as possible antiviral agents.

Wu M, El-Kattan Y, Lin TH, Ghosh A, Kumar VS, Kotian PL, Cheng X, Bantia S, Babu YS, Chand P. Wu M, et al. Among authors: el kattan y. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1569-85. doi: 10.1080/15257770500265315. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438035

8

Synthesis of 9-[1-(1 -hydroxyethyl)-3-(phosphonomethoxy)propyl]adenine and prodrug as possible antiviral agents.

Ghosh A, El-Kattan Y, Wu M, Lin TH, Vadlakonda S, Kotian PL, Babu YS, Chand P. Ghosh A, et al. Among authors: el kattan y. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1587-95. doi: 10.1080/15257770500265612. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438036

9

Synthesis of N6-substituted 9-[3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents.

El-Kattan Y, Lin TH, Wu M, Kumar VS, Kotian PL, Ghosh A, Cheng X, Bantia S, Babu YS, Chand P. El-Kattan Y, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1597-611. doi: 10.1080/15257770500265760. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438037

10

An efficient synthesis of acyclic N7- and N9-adenine nucleosides via alkylation with secondary carbon electrophiles to introduce versatile functional groups at the C-1 position of acyclic moiety.

Kotian PL, Kumar VS, Lin TH, El-Kattan Y, Ghosh A, Wu M, Cheng X, Bantia S, Babu YS, Chand P. Kotian PL, et al. Among authors: el kattan y. Nucleosides Nucleotides Nucleic Acids. 2006;25(2):121-40. doi: 10.1080/15257770500446816. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 16541957

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