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A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.
Mathur R, Choi WS, Eldstrom J, Wang Z, Kim J, Steele DF, Fedida D. Mathur R, et al. Among authors: eldstrom j. Biochem Biophys Res Commun. 2006 Mar 31;342(1):1-8. doi: 10.1016/j.bbrc.2006.01.110. Epub 2006 Jan 31. Biochem Biophys Res Commun. 2006. PMID: 16466689
We have previously reported that SAP97 enhancement of hKv1.5 currents requires an intact Kv1.5 N-terminus and is independent of the PDZ-binding motif at the C-terminus of the channel [J. Eldstrom, W.S. Choi, D.F. Steele, D. Fedida, SAP97 increases Kv1.5 currents thr …
We have previously reported that SAP97 enhancement of hKv1.5 currents requires an intact Kv1.5 N-terminus and is independent of the PDZ-bind …
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