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Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.
Peng H, Cassel J, McCracken DS, Prokop JW, Sementino E, Cheung M, Collop PR, Polo A, Joshi S, Mandell JP, Ayyanathan K, Hinds D, Malkowicz SB, Harbour JW, Bowcock AM, Salvino J, Kennedy EJ, Testa JR, Rauscher FJ 3rd. Peng H, et al. Among authors: sementino e. Mol Cancer Res. 2021 Jul;19(7):1099-1112. doi: 10.1158/1541-7786.MCR-20-0080. Epub 2021 Mar 17. Mol Cancer Res. 2021. PMID: 33731362 Free PMC article.
Germline BAP1 mutations predispose to malignant mesothelioma.
Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M. Testa JR, et al. Among authors: sementino e. Nat Genet. 2011 Aug 28;43(10):1022-5. doi: 10.1038/ng.912. Nat Genet. 2011. PMID: 21874000 Free PMC article.
Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma.
Tan Y, Sementino E, Cheung M, Peri S, Menges CW, Kukuyan AM, Zhang T, Khazak V, Fox LA, Ross EA, Ramanathan S, Jhanwar SC, Flores RM, Balachandran S, Testa JR. Tan Y, et al. Among authors: sementino e. Clin Cancer Res. 2021 Feb 15;27(4):1200-1213. doi: 10.1158/1078-0432.CCR-18-3683. Epub 2020 Nov 17. Clin Cancer Res. 2021. PMID: 33203643 Free PMC article.
21 results