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Year | Number of Results |
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2004 | 3 |
2010 | 1 |
2013 | 2 |
2020 | 1 |
2024 | 0 |
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Page 1
Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity.
ACS Med Chem Lett. 2020 Oct 16;11(12):2389-2396. doi: 10.1021/acsmedchemlett.0c00344. eCollection 2020 Dec 10.
ACS Med Chem Lett. 2020.
PMID: 33335661
Free PMC article.
Synthesis and optimization of a novel series of HCV NS3 protease inhibitors: 4-arylproline analogs.
Bilodeau F, Bailey MD, Bhardwaj PK, Bordeleau J, Forgione P, Garneau M, Ghiro E, Gorys V, Halmos T, Jolicoeur ES, Leblanc M, Lemke CT, Naud J, O'Meara J, White PW, Llinàs-Brunet M.
Bilodeau F, et al. Among authors: ghiro e.
Bioorg Med Chem Lett. 2013 Jul 15;23(14):4267-71. doi: 10.1016/j.bmcl.2013.03.043. Epub 2013 Mar 19.
Bioorg Med Chem Lett. 2013.
PMID: 23735741
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Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus.
Décor A, Grand-Maître C, Hucke O, O'Meara J, Kuhn C, Constantineau-Forget L, Brochu C, Malenfant E, Bertrand-Laperle M, Bordeleau J, Ghiro E, Pesant M, Fazal G, Gorys V, Little M, Boucher C, Bordeleau S, Turcotte P, Guo T, Garneau M, Spickler C, Gauthier A.
Décor A, et al. Among authors: ghiro e.
Bioorg Med Chem Lett. 2013 Jul 1;23(13):3841-7. doi: 10.1016/j.bmcl.2013.04.077. Epub 2013 May 7.
Bioorg Med Chem Lett. 2013.
PMID: 23726345
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Discovery of a potent and selective noncovalent linear inhibitor of the hepatitis C virus NS3 protease (BI 201335).
Llinàs-Brunet M, Bailey MD, Goudreau N, Bhardwaj PK, Bordeleau J, Bös M, Bousquet Y, Cordingley MG, Duan J, Forgione P, Garneau M, Ghiro E, Gorys V, Goulet S, Halmos T, Kawai SH, Naud J, Poupart MA, White PW.
Llinàs-Brunet M, et al. Among authors: ghiro e.
J Med Chem. 2010 Sep 9;53(17):6466-76. doi: 10.1021/jm100690x.
J Med Chem. 2010.
PMID: 20715823
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Synthesis of BILN 2061, an HCV NS3 protease inhibitor with proven antiviral effect in humans.
Faucher AM, Bailey MD, Beaulieu PL, Brochu C, Duceppe JS, Ferland JM, Ghiro E, Gorys V, Halmos T, Kawai SH, Poirier M, Simoneau B, Tsantrizos YS, Llinàs-Brunet M.
Faucher AM, et al. Among authors: ghiro e.
Org Lett. 2004 Aug 19;6(17):2901-4. doi: 10.1021/ol0489907.
Org Lett. 2004.
PMID: 15330643
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Structure-activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061.
Llinàs-Brunet M, Bailey MD, Bolger G, Brochu C, Faucher AM, Ferland JM, Garneau M, Ghiro E, Gorys V, Grand-Maître C, Halmos T, Lapeyre-Paquette N, Liard F, Poirier M, Rhéaume M, Tsantrizos YS, Lamarre D.
Llinàs-Brunet M, et al. Among authors: ghiro e.
J Med Chem. 2004 Mar 25;47(7):1605-8. doi: 10.1021/jm0342414.
J Med Chem. 2004.
PMID: 15027850
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A systematic approach to the optimization of substrate-based inhibitors of the hepatitis C virus NS3 protease: discovery of potent and specific tripeptide inhibitors.
Llinàs-Brunet M, Bailey MD, Ghiro E, Gorys V, Halmos T, Poirier M, Rancourt J, Goudreau N.
Llinàs-Brunet M, et al. Among authors: ghiro e.
J Med Chem. 2004 Dec 16;47(26):6584-94. doi: 10.1021/jm0494523.
J Med Chem. 2004.
PMID: 15588093
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