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Page 1
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment.
Cancer Cell. 2021 Nov 8;39(11):1464-1478.e8. doi: 10.1016/j.ccell.2021.09.005. Epub 2021 Oct 15.
Cancer Cell. 2021.
PMID: 34719426
Free PMC article.
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf RZ, Saez B, Sharda A, van Gastel N, Yu VWC, Baryawno N, Scadden EW, Acharya S, Chattophadhyay S, Huang C, Viswanathan V, S'aulis D, Cobert J, Sykes DB, Keibler MA, Das S, Hutchinson JN, Churchill M, Mukherjee S, Lee D, Mercier F, Doench J, Bullinger L, Logan DJ, Schreiber S, Stephanopoulos G, Rizzo WB, Scadden DT.
Yusuf RZ, et al. Among authors: scadden ew.
Blood. 2020 Sep 10;136(11):1303-1316. doi: 10.1182/blood.2019001808.
Blood. 2020.
PMID: 32458004
Free PMC article.
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Clearing and replacing tissue-resident myeloid cells with an anti-CD45 antibody-drug conjugate.
Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy SL, Boitano AE, Nahrendorf M, Scadden DT.
Gustafsson K, et al. Among authors: scadden ew.
Blood Adv. 2023 Nov 28;7(22):6964-6973. doi: 10.1182/bloodadvances.2023010561.
Blood Adv. 2023.
PMID: 37748049
Free PMC article.
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Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors.
Rhee C, Scadden EW, Wong LP, Schiroli G, Mazzola MC, Chea PL, Kato H, Hoyer FF, Mistry M, Lee BK, Kim J, Nahrendorf M, Mansour MK, Sykes DB, Sadreyev RI, Scadden DT.
Rhee C, et al. Among authors: scadden ew.
Blood. 2023 Aug 17;142(7):658-674. doi: 10.1182/blood.2023020257.
Blood. 2023.
PMID: 37267513
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Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance.
Çoku J, Booth DM, Skoda J, Pedrotty MC, Vogel J, Liu K, Vu A, Carpenter EL, Ye JC, Chen MA, Dunbar P, Scadden E, Yun TD, Nakamaru-Ogiso E, Area-Gomez E, Li Y, Goldsmith KC, Reynolds CP, Hajnoczky G, Hogarty MD.
Çoku J, et al. Among authors: scadden e.
EMBO J. 2022 Apr 19;41(8):e108272. doi: 10.15252/embj.2021108272. Epub 2022 Feb 25.
EMBO J. 2022.
PMID: 35211994
Free PMC article.
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CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer.
Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy SL, Boitano AE, Nahrendorf M, Scadden DT.
Gustafsson K, et al. Among authors: scadden ew.
bioRxiv [Preprint]. 2023 Sep 7:2023.09.05.556397. doi: 10.1101/2023.09.05.556397.
bioRxiv. 2023.
PMID: 37732224
Free PMC article.
Preprint.
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Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.
Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT.
Severe N, et al. Among authors: scadden ew.
Cell Stem Cell. 2019 Oct 3;25(4):570-583.e7. doi: 10.1016/j.stem.2019.06.003. Epub 2019 Jul 3.
Cell Stem Cell. 2019.
PMID: 31279774
Free PMC article.
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