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Page 1
Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis.
Enukashvily NI, Ponomartsev NV, Ketkar A, Suezov R, Chubar AV, Prjibelski AD, Shafranskaya DD, Elmshäuser S, Keber CU, Stefanova VN, Akopov AL, Klingmüller U, Pfefferle PI, Stiewe T, Lauth M, Brichkina AI. Enukashvily NI, et al. Among authors: elmshauser s. Cell Death Dis. 2023 Jan 12;14(1):19. doi: 10.1038/s41419-023-05553-1. Cell Death Dis. 2023. PMID: 36635266 Free PMC article.
p53 partial loss-of-function mutations sensitize to chemotherapy.
Klimovich B, Merle N, Neumann M, Elmshäuser S, Nist A, Mernberger M, Kazdal D, Stenzinger A, Timofeev O, Stiewe T. Klimovich B, et al. Among authors: elmshauser s. Oncogene. 2022 Feb;41(7):1011-1023. doi: 10.1038/s41388-021-02141-5. Epub 2021 Dec 14. Oncogene. 2022. PMID: 34907344 Free PMC article.
Partial p53 reactivation is sufficient to induce cancer regression.
Klimovich B, Meyer L, Merle N, Neumann M, König AM, Ananikidis N, Keber CU, Elmshäuser S, Timofeev O, Stiewe T. Klimovich B, et al. Among authors: elmshauser s. J Exp Clin Cancer Res. 2022 Mar 2;41(1):80. doi: 10.1186/s13046-022-02269-6. J Exp Clin Cancer Res. 2022. PMID: 35232479 Free PMC article.
Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging.
Timofeev O, Koch L, Niederau C, Tscherne A, Schneikert J, Klimovich M, Elmshäuser S, Zeitlinger M, Mernberger M, Nist A, Osterburg C, Dötsch V, Hrabé de Angelis M, Stiewe T; German Mouse Clinic Consortium. Timofeev O, et al. Among authors: elmshauser s. Cancer Res. 2020 Dec 1;80(23):5231-5244. doi: 10.1158/0008-5472.CAN-20-2002. Epub 2020 Sep 1. Cancer Res. 2020. PMID: 32873634
Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase.
Merle N, Elmshäuser S, Strassheimer F, Wanzel M, König AM, Funk J, Neumann M, Kochhan K, Helmprobst F, Pagenstecher A, Nist A, Mernberger M, Schneider A, Braun T, Borggrefe T, Savai R, Timofeev O, Stiewe T. Merle N, et al. Among authors: elmshauser s. Mol Cancer. 2022 Oct 3;21(1):191. doi: 10.1186/s12943-022-01661-2. Mol Cancer. 2022. PMID: 36192757 Free PMC article.
Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses.
Timofeev O, Klimovich B, Schneikert J, Wanzel M, Pavlakis E, Noll J, Mutlu S, Elmshäuser S, Nist A, Mernberger M, Lamp B, Wenig U, Brobeil A, Gattenlöhner S, Köhler K, Stiewe T. Timofeev O, et al. Among authors: elmshauser s. EMBO J. 2019 Oct 15;38(20):e102096. doi: 10.15252/embj.2019102096. Epub 2019 Sep 4. EMBO J. 2019. PMID: 31483066 Free PMC article.