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A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling.
Mol Cell. 2023 Aug 3;83(15):2692-2708.e7. doi: 10.1016/j.molcel.2023.06.024. Epub 2023 Jul 20.
Mol Cell. 2023.
PMID: 37478845
Free article.
Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models.
Jones CJ, Subramaniam M, Emch MJ, Bruinsma ES, Ingle JN, Goetz MP, Hawse JR.
Jones CJ, et al. Among authors: emch mj.
Mol Cancer Res. 2021 Jun;19(6):1026-1039. doi: 10.1158/1541-7786.MCR-20-0872. Epub 2021 Feb 24.
Mol Cancer Res. 2021.
PMID: 33627502
Free PMC article.
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Disruption of estrogen receptor beta's DNA binding domain impairs its tumor suppressive effects in triple negative breast cancer.
Aspros KGM, Emch MJ, Wang X, Subramaniam M, Hinkle ML, Rodman EPB, Goetz MP, Hawse JR.
Aspros KGM, et al. Among authors: emch mj.
Front Med (Lausanne). 2023 Feb 28;10:1047166. doi: 10.3389/fmed.2023.1047166. eCollection 2023.
Front Med (Lausanne). 2023.
PMID: 36926316
Free PMC article.
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Estrogen-regulated miRs in bone enhance osteoblast differentiation and matrix mineralization.
Emch MJ, Wicik Z, Aspros KGM, Vukajlovic T, Pitel KS, Narum AK, Weivoda MM, Tang X, Kalari KR, Turner RT, Iwaniec UT, Monroe DG, Subramaniam M, Hawse JR.
Emch MJ, et al.
Mol Ther Nucleic Acids. 2023 Jun 3;33:28-41. doi: 10.1016/j.omtn.2023.05.026. eCollection 2023 Sep 12.
Mol Ther Nucleic Acids. 2023.
PMID: 37359348
Free PMC article.
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Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer.
Aspros KGM, Carter JM, Hoskin TL, Suman VJ, Subramaniam M, Emch MJ, Ye Z, Sun Z, Sinnwell JP, Thompson KJ, Tang X, Rodman EPB, Wang X, Nelson AW, Chernukhin I, Hamdan FH, Bruinsma ES, Carroll JS, Fernandez-Zapico ME, Johnsen SA, Kalari KR, Huang H, Leon-Ferre RA, Couch FJ, Ingle JN, Goetz MP, Hawse JR.
Aspros KGM, et al. Among authors: emch mj.
NPJ Breast Cancer. 2022 Feb 17;8(1):20. doi: 10.1038/s41523-022-00387-0.
NPJ Breast Cancer. 2022.
PMID: 35177654
Free PMC article.
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Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells.
Wierson WA, Simone BW, WareJoncas Z, Mann C, Welker JM, Kar B, Emch MJ, Friedberg I, Gendron WAC, Barry MA, Clark KJ, Dobbs DL, McGrail MA, Ekker SC, Essner JJ.
Wierson WA, et al. Among authors: emch mj.
CRISPR J. 2019 Dec;2(6):417-433. doi: 10.1089/crispr.2019.0026. Epub 2019 Nov 19.
CRISPR J. 2019.
PMID: 31742435
Free PMC article.
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