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PRIMPOL ready, set, reprime!
Tirman S, Cybulla E, Quinet A, Meroni A, Vindigni A. Tirman S, et al. Among authors: cybulla e. Crit Rev Biochem Mol Biol. 2021 Feb;56(1):17-30. doi: 10.1080/10409238.2020.1841089. Epub 2020 Nov 12. Crit Rev Biochem Mol Biol. 2021. PMID: 33179522 Free PMC article. Review.
To skip or not to skip: choosing repriming to tolerate DNA damage.
Quinet A, Tirman S, Cybulla E, Meroni A, Vindigni A. Quinet A, et al. Among authors: cybulla e. Mol Cell. 2021 Feb 18;81(4):649-658. doi: 10.1016/j.molcel.2021.01.012. Epub 2021 Jan 29. Mol Cell. 2021. PMID: 33515486 Free PMC article. Review.
GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition through Increased DNA Damage and Enhanced Replication Stress.
Mullen MM, Lomonosova E, Toboni MD, Oplt A, Cybulla E, Blachut B, Zhao P, Noia H, Wilke D, Rankin EB, Kuroki LM, Hagemann AR, Hagemann IS, McCourt CK, Thaker PH, Mutch DG, Powell MA, Mosammaparast N, Vindigni A, Fuh KC. Mullen MM, et al. Among authors: cybulla e. Mol Cancer Res. 2022 Feb;20(2):265-279. doi: 10.1158/1541-7786.MCR-21-0302. Epub 2021 Oct 20. Mol Cancer Res. 2022. PMID: 34670865 Free PMC article.
PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells.
Quinet A, Tirman S, Jackson J, Šviković S, Lemaçon D, Carvajal-Maldonado D, González-Acosta D, Vessoni AT, Cybulla E, Wood M, Tavis S, Batista LFZ, Méndez J, Sale JE, Vindigni A. Quinet A, et al. Among authors: cybulla e. Mol Cell. 2020 Feb 6;77(3):461-474.e9. doi: 10.1016/j.molcel.2019.10.008. Epub 2019 Oct 29. Mol Cell. 2020. PMID: 31676232 Free PMC article.
Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer.
Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, Khabele D. Gupta VG, et al. Among authors: cybulla e. Gynecol Oncol. 2021 Jul;162(1):163-172. doi: 10.1016/j.ygyno.2021.04.015. Epub 2021 Apr 16. Gynecol Oncol. 2021. PMID: 33867143 Free PMC article.