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Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma.
Huuhtanen J, Kasanen H, Peltola K, Lönnberg T, Glumoff V, Brück O, Dufva O, Peltonen K, Vikkula J, Jokinen E, Ilander M, Lee MH, Mäkelä S, Nyakas M, Li B, Hernberg M, Bono P, Lähdesmäki H, Kreutzman A, Mustjoki S. Huuhtanen J, et al. Among authors: jokinen e. J Clin Invest. 2023 Mar 15;133(6):e164809. doi: 10.1172/JCI164809. J Clin Invest. 2023. PMID: 36719749 Free PMC article.
Evolution and modulation of antigen-specific T cell responses in melanoma patients.
Huuhtanen J, Chen L, Jokinen E, Kasanen H, Lönnberg T, Kreutzman A, Peltola K, Hernberg M, Wang C, Yee C, Lähdesmäki H, Davis MM, Mustjoki S. Huuhtanen J, et al. Among authors: jokinen e. Nat Commun. 2022 Oct 11;13(1):5988. doi: 10.1038/s41467-022-33720-z. Nat Commun. 2022. PMID: 36220826 Free PMC article.
TSignal: a transformer model for signal peptide prediction.
Dumitrescu A, Jokinen E, Paatero A, Kellosalo J, Paavilainen VO, Lähdesmäki H. Dumitrescu A, et al. Among authors: jokinen e. Bioinformatics. 2023 Jun 30;39(39 Suppl 1):i347-i356. doi: 10.1093/bioinformatics/btad228. Bioinformatics. 2023. PMID: 37387131 Free PMC article.
Substrate specificity of 2-deoxy-D-ribose 5-phosphate aldolase (DERA) assessed by different protein engineering and machine learning methods.
Voutilainen S, Heinonen M, Andberg M, Jokinen E, Maaheimo H, Pääkkönen J, Hakulinen N, Rouvinen J, Lähdesmäki H, Kaski S, Rousu J, Penttilä M, Koivula A. Voutilainen S, et al. Among authors: jokinen e. Appl Microbiol Biotechnol. 2020 Dec;104(24):10515-10529. doi: 10.1007/s00253-020-10960-x. Epub 2020 Nov 4. Appl Microbiol Biotechnol. 2020. PMID: 33147349 Free PMC article.