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Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation.
Trends Mol Med. 2021 Dec;27(12):1135-1158. doi: 10.1016/j.molmed.2021.09.006. Epub 2021 Oct 14.
Trends Mol Med. 2021.
PMID: 34657800
Review.
Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity.
Shim WJ, Sinniah E, Xu J, Vitrinel B, Alexanian M, Andreoletti G, Shen S, Sun Y, Balderson B, Boix C, Peng G, Jing N, Wang Y, Kellis M, Tam PPL, Smith A, Piper M, Christiaen L, Nguyen Q, Bodén M, Palpant NJ.
Shim WJ, et al. Among authors: sinniah e.
Cell Syst. 2020 Dec 16;11(6):625-639.e13. doi: 10.1016/j.cels.2020.11.001. Epub 2020 Dec 4.
Cell Syst. 2020.
PMID: 33278344
Free PMC article.
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Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1-3 in mesendoderm cell differentiation.
Sinniah E, Wu Z, Shen S, Naval-Sanchez M, Chen X, Lim J, Helfer A, Iyer A, Tng J, Lucke AJ, Reid RC, Redd MA, Nefzger CM, Fairlie DP, Palpant NJ.
Sinniah E, et al.
Cell Rep. 2022 May 17;39(7):110818. doi: 10.1016/j.celrep.2022.110818.
Cell Rep. 2022.
PMID: 35584683
Free article.
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Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Kojic M, Gawda T, Gaik M, Begg A, Salerno-Kochan A, Kurniawan ND, Jones A, Drożdżyk K, Kościelniak A, Chramiec-Głąbik A, Hediyeh-Zadeh S, Kasherman M, Shim WJ, Sinniah E, Genovesi LA, Abrahamsen RK, Fenger CD, Madsen CG, Cohen JS, Fatemi A, Stark Z, Lunke S, Lee J, Hansen JK, Boxill MF, Keren B, Marey I, Saenz MS, Brown K, Alexander SA, Mureev S, Batzilla A, Davis MJ, Piper M, Bodén M, Burne THJ, Palpant NJ, Møller RS, Glatt S, Wainwright BJ.
Kojic M, et al. Among authors: sinniah e.
Nat Commun. 2021 May 11;12(1):2678. doi: 10.1038/s41467-021-22888-5.
Nat Commun. 2021.
PMID: 33976153
Free PMC article.
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Inferring cell diversity in single cell data using consortium-scale epigenetic data as a biological anchor for cell identity.
Sun Y, Shim WJ, Shen S, Sinniah E, Pham D, Su Z, Mizikovsky D, White MD, Ho JWK, Nguyen Q, Bodén M, Palpant NJ.
Sun Y, et al. Among authors: sinniah e.
Nucleic Acids Res. 2023 Jun 23;51(11):e62. doi: 10.1093/nar/gkad307.
Nucleic Acids Res. 2023.
PMID: 37125641
Free PMC article.
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