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The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner.
Meinhardt AL, Munkhbaatar E, Höckendorf U, Dietzen M, Dechant M, Anton M, Jacob A, Steiger K, Weichert W, Brcic L, McGranahan N, Branca C, Kaufmann T, Dengler MA, Jost PJ. Meinhardt AL, et al. Among authors: munkhbaatar e. Oncogene. 2022 Feb;41(9):1376-1382. doi: 10.1038/s41388-021-02161-1. Epub 2022 Jan 29. Oncogene. 2022. PMID: 35091677 Free PMC article.
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes.
Eckfeld C, Schoeps B, Häußler D, Frädrich J, Bayerl F, Böttcher JP, Knolle P, Heisz S, Prokopchuk O, Hauner H, Munkhbaatar E, Demir IE, Hermann CD, Krüger A. Eckfeld C, et al. Among authors: munkhbaatar e. J Cell Biol. 2023 Feb 6;222(2):e202206095. doi: 10.1083/jcb.202206095. Epub 2023 Jan 11. J Cell Biol. 2023. PMID: 36629908 Free PMC article.
TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer.
Hermann CD, Schoeps B, Eckfeld C, Munkhbaatar E, Kniep L, Prokopchuk O, Wirges N, Steiger K, Häußler D, Knolle P, Poulton E, Khokha R, Grünwald BT, Demir IE, Krüger A. Hermann CD, et al. Among authors: munkhbaatar e. J Exp Med. 2021 Nov 1;218(11):e20210911. doi: 10.1084/jem.20210911. Epub 2021 Sep 17. J Exp Med. 2021. PMID: 34533565 Free PMC article.
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.
Munkhbaatar E, Dietzen M, Agrawal D, Anton M, Jesinghaus M, Boxberg M, Pfarr N, Bidola P, Uhrig S, Höckendorf U, Meinhardt AL, Wahida A, Heid I, Braren R, Mishra R, Warth A, Muley T, Poh PSP, Wang X, Fröhling S, Steiger K, Slotta-Huspenina J, van Griensven M, Pfeiffer F, Lange S, Rad R, Spella M, Stathopoulos GT, Ruland J, Bassermann F, Weichert W, Strasser A, Branca C, Heikenwalder M, Swanton C, McGranahan N, Jost PJ. Munkhbaatar E, et al. Nat Commun. 2020 Sep 10;11(1):4527. doi: 10.1038/s41467-020-18372-1. Nat Commun. 2020. PMID: 32913197 Free PMC article.
RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
Höckendorf U, Yabal M, Herold T, Munkhbaatar E, Rott S, Jilg S, Kauschinger J, Magnani G, Reisinger F, Heuser M, Kreipe H, Sotlar K, Engleitner T, Rad R, Weichert W, Peschel C, Ruland J, Heikenwalder M, Spiekermann K, Slotta-Huspenina J, Groß O, Jost PJ. Höckendorf U, et al. Among authors: munkhbaatar e. Cancer Cell. 2016 Jul 11;30(1):75-91. doi: 10.1016/j.ccell.2016.06.002. Cancer Cell. 2016. PMID: 27411587 Free article.