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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2004 2
2005 1
2006 4
2007 5
2008 2
2009 2
2010 4
2011 2
2012 3
2013 5
2014 4
2015 3
2016 3
2017 6
2018 5
2019 3
2020 3
2021 4
2022 3
2023 1
2024 1

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60 results

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Page 1
Ligand and Target Discovery by Fragment-Based Screening in Human Cells.
Parker CG, Galmozzi A, Wang Y, Correia BE, Sasaki K, Joslyn CM, Kim AS, Cavallaro CL, Lawrence RM, Johnson SR, Narvaiza I, Saez E, Cravatt BF. Parker CG, et al. Among authors: saez e. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19. Cell. 2017. PMID: 28111073 Free PMC article.
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.
Bar-Peled L, Kemper EK, Suciu RM, Vinogradova EV, Backus KM, Horning BD, Paul TA, Ichu TA, Svensson RU, Olucha J, Chang MW, Kok BP, Zhu Z, Ihle NT, Dix MM, Jiang P, Hayward MM, Saez E, Shaw RJ, Cravatt BF. Bar-Peled L, et al. Among authors: saez e. Cell. 2017 Oct 19;171(3):696-709.e23. doi: 10.1016/j.cell.2017.08.051. Epub 2017 Sep 28. Cell. 2017. PMID: 28965760 Free PMC article.
PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Galmozzi A, Kok BP, Kim AS, Montenegro-Burke JR, Lee JY, Spreafico R, Mosure S, Albert V, Cintron-Colon R, Godio C, Webb WR, Conti B, Solt LA, Kojetin D, Parker CG, Peluso JJ, Pru JK, Siuzdak G, Cravatt BF, Saez E. Galmozzi A, et al. Among authors: saez e. Nature. 2019 Dec;576(7785):138-142. doi: 10.1038/s41586-019-1774-2. Epub 2019 Nov 20. Nature. 2019. PMID: 31748741 Free PMC article.
Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension.
Rinschen MM, Palygin O, El-Meanawy A, Domingo-Almenara X, Palermo A, Dissanayake LV, Golosova D, Schafroth MA, Guijas C, Demir F, Jaegers J, Gliozzi ML, Xue J, Hoehne M, Benzing T, Kok BP, Saez E, Bleich M, Himmerkus N, Weisz OA, Cravatt BF, Krüger M, Benton HP, Siuzdak G, Staruschenko A. Rinschen MM, et al. Among authors: saez e. Nat Commun. 2022 Jul 14;13(1):4099. doi: 10.1038/s41467-022-31670-0. Nat Commun. 2022. PMID: 35835746 Free PMC article.
Zc3h10 is a novel mitochondrial regulator.
Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia GR, Ghisletti S, Cuomo A, Bonaldi T, Salerno F, Mora M, Grigore L, Garlaschelli K, Baragetti A, Bonacina F, Catapano AL, Norata GD, Crestani M, Caruso D, Saez E, De Fabiani E, Mitro N. Audano M, et al. Among authors: saez e. EMBO Rep. 2018 Apr;19(4):e45531. doi: 10.15252/embr.201745531. Epub 2018 Mar 5. EMBO Rep. 2018. PMID: 29507079 Free PMC article.
NIH Workshop Report: sensory nutrition and disease.
Reed DR, Alhadeff AL, Beauchamp GK, Chaudhari N, Duffy VB, Dus M, Fontanini A, Glendinning JI, Green BG, Joseph PV, Kyriazis GA, Lyte M, Maruvada P, McGann JP, McLaughlin JT, Moran TH, Murphy C, Noble EE, Pepino MY, Pluznick JL, Rother KI, Saez E, Spector AC, Sternini C, Mattes RD. Reed DR, et al. Among authors: saez e. Am J Clin Nutr. 2021 Jan 4;113(1):232-245. doi: 10.1093/ajcn/nqaa302. Am J Clin Nutr. 2021. PMID: 33300030 Free PMC article.
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly.
Stanton C, Sun J, Nutsch K, Rosarda JD, Nguyen T, Li-Ma C, Njomen E, Melillo B, Kutseikin S, Saez E, Cravatt BF, Teijaro JR, Wiseman RL, Bollong MJ. Stanton C, et al. Among authors: saez e. ACS Chem Biol. 2024 Feb 16;19(2):254-265. doi: 10.1021/acschembio.3c00330. Epub 2024 Jan 10. ACS Chem Biol. 2024. PMID: 38198472
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Kok BP, Ghimire S, Kim W, Chatterjee S, Johns T, Kitamura S, Eberhardt J, Ogasawara D, Xu J, Sukiasyan A, Kim SM, Godio C, Bittencourt JM, Cameron M, Galmozzi A, Forli S, Wolan DW, Cravatt BF, Boger DL, Saez E. Kok BP, et al. Among authors: saez e. Nat Chem Biol. 2020 Sep;16(9):997-1005. doi: 10.1038/s41589-020-0555-4. Epub 2020 Jun 8. Nat Chem Biol. 2020. PMID: 32514184 Free PMC article.
60 results